$91 Cheap Flights from Minneapolis (MSP) to Des Moines (DSM)

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Find available prices by choosing your travel dates.

Cheap Flights from Minneapolis to Des Moines (MSP-DSM)

Prices were available within the past 7 days and start at $91 for one-way flights and $180 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Delta
Frontier Airlines
Frontier Airlines
United
American Airlines
Southwest Airlines
Flights from Minneapolis (MSP) to Des Moines (DSM)
Origin airport
Minneapolis - St. Paul Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$180
Distance
232 mi

Minneapolis to Des Moines Flights

The cheapest times to fly from Minneapolis to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Minneapolis to Des Moines are during the month of May. You can find some of the cheapest flights from Minneapolis to Des Moines with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Minneapolis to Des Moines

Sunday is one of the best days to book for cheap flights from Minneapolis to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Minneapolis to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Minneapolis to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $91 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Minneapolis to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Minneapolis to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM) cost?
Cheap return fares from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM) start at $199. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Delta flight leaving MSP on May 17 2025 and touching down at DSM. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from MSP to DSM?
The cheapest flights from MSP to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM)?
Fly nonstop from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM) on a Delta Air Lines flight.
What is the cheapest airline that flies from MSP to DSM?
With tickets starting at $229 for a one-way flight from MSP to DSM, Delta is currently the cheapest airline flying this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MSP on June 6 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM)?
When taking off from Minneapolis - St. Paul Intl. Airport (MSP), you’ll have a choice from an average of 2 daily nonstop flights to Des Moines Intl. Airport (DSM).
What are the most popular departure times for flights from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM)?
Flights between MSP and DSM are busiest at 7 PM. If you’d like a more relaxed atmosphere and possibly cheaper prices, look for a departure outside the usual busy windows.
What day of the week has the most flights from MSP to DSM?
Jet off on a Friday if you’re looking for the biggest selection of flights from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM).
What is the earliest flight from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM)?
Catch the earliest flight at around 10:10AM UTC-6, heading out of Minneapolis - St. Paul Intl. Airport (MSP). You’ll be flying for around 1h 21m, coming in to land at Des Moines Intl. Airport (DSM) at approximately 11:31AM UTC-6.
How long does it take to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM)?
The average flight duration from MSP to DSM is 1 hour and 18 minutes, covering a distance of 230 mi.
What airline has the least delays from MSP to DSM?
With 100% of flights generally landing on schedule, American Airlines has the best on-time performance for direct flights from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM). To check your flight status and receive notifications about any changes, simply head to the Expedia App.
What is the best time to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM)?
Opt for a flight from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Des Moines from Minneapolis - St. Paul Intl. Airport (MSP)?
If you’re on a direct flight from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines, Des Moines Intl. Airport (DSM) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from MSP to DSM are generally more expensive. To lock in the best rates, start searching for flights ahead of time. That said, if you can play around with your travel dates, you may score a cheap fare right before you leave.
Is it cheaper to book a MSP to DSM flight and hotel package?
Compared with arranging flights and hotels separately, booking a MSP to DSM flight and hotel package with Expedia could lead to significant savings. What’s more, having everything in one place will take the hassle out of travel planning. Just pick your flights and select from our wide range of stays, then customize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Minneapolis - St. Paul Intl. Airport (MSP) to Des Moines Intl. Airport (DSM)?
In most cases, you can reschedule or cancel your MSP to DSM flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline’s fees and policies on flight changes, or if you want more information, visit our Customer Service portal.

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