$115 Cheap Flights from Moline (MLI) to San Diego (SAN)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
Find available prices by choosing your travel dates.

Cheap Flights from Moline to San Diego (MLI-SAN)

Prices were available within the past 7 days and start at $115 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
United
United
United
United
American Airlines
United
American Airlines
Delta
Alaska Airlines
Flights from Moline (MLI) to San Diego (SAN)
Origin airport
Quad City Intl.
Destination airport
San Diego Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, United
Roundtrip price
$228
Distance
1581 mi

Moline to San Diego Flights

The cheapest times to fly from Moline to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Moline to San Diego are during the month of May. You can find some of the cheapest flights from Moline to San Diego with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Moline to San Diego

Sunday is one of the best days to book for cheap flights from Moline to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Moline to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Moline to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from $115 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Moline to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Moline to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

Is it cheaper to buy a plane ticket from Quad City Intl. Airport (MLI) to SAN last minute?
Being spontaneous is a fantastic way to discover the world, but it isn’t always the wisest way to land a bargain plane ticket. It’s better to book your Quad City Intl. Airport (MLI) to SAN trip ahead of time rather than leaving it to the last minute. Based on flight pricing and demand studies in 2022, we have found that the best time to book domestic flights is between 28 – 35 days ahead of the departure date, and international flights three to four months in advance. Save up that spontaneity for when you reach your destination!
What airports do you fly into for San Diego from Moline?
With San Diego Intl. Airport (SAN), McClellan-Palomar Airport (CLD) and San Diego, CA (MYF-Montgomery Field) to pick from, flying from Moline to San Diego is a breeze. The city’s busiest terminal, San Diego Intl. Airport (SAN), is roughly 2 mi northwest of the center. Along with ticket costs, consider things like public transportation options from the airport and the distance to your hotel before making your decision. Get your San Diego adventure off on the right foot by exploring San Diego Zoo and Balboa Park.
Can I change the date of my flight from Quad City Intl. Airport (MLI) to San Diego Airport?
Plans can get upended, so Expedia is here to help make amending your journey as easy as possible. First, access your MLI to San Diego Intl. Airport (SAN) itinerary through the Expedia Trips portal and browse the fare conditions to see if change fees apply. If you purchased your fare in the last 24 hours, some airlines allow you to cancel at no cost and book new flights. If you booked more than 24 hours ago, contact us through our Customer Service portal so we can assist you further.

Explore a world of travel with Expedia

*Available to One Key members.