$113 Cheap Flights from Milwaukee (MKE) to Charleston (CHS)

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Find available prices by choosing your travel dates.

Cheap Flights from Milwaukee to Charleston (MKE-CHS)

Prices were available within the past 7 days and start at $113 for one-way flights and $259 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
JetBlue Airways
United
Southwest Airlines
United
Delta
American Airlines
Delta
Spirit Airlines
Delta
Flights from Milwaukee (MKE) to Charleston (CHS)
Origin airport
General Mitchell Intl.
Destination airport
Charleston Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, Southwest Airlines, United
Roundtrip price
$258
Distance
815 mi

Milwaukee to Charleston Flights

The cheapest times to fly from Milwaukee to Charleston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Milwaukee to Charleston are during the month of May. You can find some of the cheapest flights from Milwaukee to Charleston with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Milwaukee to Charleston

Sunday is one of the best days to book for cheap flights from Milwaukee to Charleston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Milwaukee to Charleston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Milwaukee to Charleston in 2025. You can also book with separate airlines for your outbound and return journeys, from $113 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Milwaukee to Charleston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Milwaukee to Charleston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

Is it cheaper to buy a plane ticket from General Mitchell Intl. Airport (MKE) to CHS last minute?
Being the spontaneous type is a great way to discover the world, but it’s not always the best method to find a bargain flight. Think about booking your General Mitchell Intl. Airport (MKE) to CHS trip well in advance instead of waiting until the last minute. Based on flight pricing and demand studies in 2022, we have found that the best time to book domestic flights is between 28 – 35 days ahead of the departure date, and international flights three to four months in advance. Leave your spontaneity for when you’re exploring CHS!
What airports do you fly into for Charleston from Milwaukee?
Charleston Intl. Airport (CHS), Hilton Head Island Airport (HHH) and Beaufort, SC (BFT-Frogmore Intl.) are your choices when flying from Milwaukee to Charleston. Approximately 9 mi northwest of downtown Charleston, Charleston Intl. Airport (CHS) is the city’s major hub. Take into account factors such as flight schedules and the distance to your hotel before deciding on an airport. USS Yorktown and Charleston City Market are two awesome attractions to put on your to-do list when you arrive.
Can I change the date of my flight from MKE to Charleston Intl. Airport (CHS)?
Quickly and easily make changes to your MKE to Charleston Intl. Airport trip through the Expedia Trips portal. Before you make any amendments, read over the fare conditions in your itinerary to see what the carrier will allow you to do and what fees apply for changes. Some airlines have a change fee per person, in addition to any difference in fares. But if you booked in the last 24 hours, you may be able to cancel for free and organize new flights. You can also find your way to our Customer Service portal for more information and to chat with our Virtual Agent.

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*Available to One Key members.