$94 Cheap Flights from Medford (MFR) to San Francisco (SFO)

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Cheap Flights from Medford to San Francisco (MFR-SFO)

Prices were available within the past 7 days and start at $94 for one-way flights and $189 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, Jul 4 - Sat, Jul 5
MFR
Medford
SFO
San Francisco
$189 Roundtrip, just found
$189
Roundtrip
just found
Select United flight, departing Fri, Jul 4 from Medford to San Francisco, returning Sat, Jul 5, priced at $189 just found
Alaska Airlines
Thu, May 8 - Tue, May 20
MFR
Medford
SFO
San Francisco
$194 Roundtrip, found 6 hours ago
$194
Roundtrip
found 6 hours ago
Select Alaska Airlines flight, departing Thu, May 8 from Medford to San Francisco, returning Tue, May 20, priced at $194 found 6 hours ago
United
Tue, May 13 - Sun, May 18
MFR
Medford
SFO
San Francisco
$194 Roundtrip, found 9 hours ago
$194
Roundtrip
found 9 hours ago
Select United flight, departing Tue, May 13 from Medford to San Francisco, returning Sun, May 18, priced at $194 found 9 hours ago
Alaska Airlines
Fri, May 9 - Sat, May 10
MFR
Medford
SFO
San Francisco
$199 Roundtrip, found 1 hour ago
$199
Roundtrip
found 1 hour ago
Select Alaska Airlines flight, departing Fri, May 9 from Medford to San Francisco, returning Sat, May 10, priced at $199 found 1 hour ago
United
Wed, May 7 - Sat, May 10
MFR
Medford
SFO
San Francisco
$199 Roundtrip, found 1 day ago
$199
Roundtrip
found 1 day ago
Select United flight, departing Wed, May 7 from Medford to San Francisco, returning Sat, May 10, priced at $199 found 1 day ago
Alaska Airlines
Tue, Sep 30 - Sat, Oct 4
MFR
Medford
SFO
San Francisco
$208 Roundtrip, just found
$208
Roundtrip
just found
Select Alaska Airlines flight, departing Tue, Sep 30 from Medford to San Francisco, returning Sat, Oct 4, priced at $208 just found
Alaska Airlines
Thu, May 8 - Fri, May 16
MFR
Medford
SFO
San Francisco
$213 Roundtrip, found 6 hours ago
$213
Roundtrip
found 6 hours ago
Select Alaska Airlines flight, departing Thu, May 8 from Medford to San Francisco, returning Fri, May 16, priced at $213 found 6 hours ago
United
Fri, May 9 - Sat, May 10
MFR
Medford
SFO
San Francisco
$217 Roundtrip, found 4 days ago
$217
Roundtrip
found 4 days ago
Select United flight, departing Fri, May 9 from Medford to San Francisco, returning Sat, May 10, priced at $217 found 4 days ago
Alaska Airlines
Fri, May 9 - Sat, May 10
MFR
Medford
SFO
San Francisco
$218 Roundtrip, found 1 hour ago
$218
Roundtrip
found 1 hour ago
Select Alaska Airlines flight, departing Fri, May 9 from Medford to San Francisco, returning Sat, May 10, priced at $218 found 1 hour ago
American Airlines
Tue, May 13 - Fri, May 16
MFR
Medford
SFO
San Francisco
$285 Roundtrip, found 5 days ago
$285
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, May 13 from Medford to San Francisco, returning Fri, May 16, priced at $285 found 5 days ago
Flights from Medford (MFR) to San Francisco (SFO)
Origin airport
Rogue Valley Intl.
Destination airport
San Francisco Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Hawaiian Airlines, United
Roundtrip price
$182
Distance
329 mi

Medford to San Francisco Flights

The cheapest times to fly from Medford to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medford to San Francisco are during the month of July. You can find some of the cheapest flights from Medford to San Francisco with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Medford to San Francisco

Sunday is one of the best days to book for cheap flights from Medford to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Medford to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medford to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $94 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medford to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medford to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO) cost?
Cheap round-trip flights from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO) start at $189. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a United flight leaving MFR on May 17 2025 and touching down at SFO. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from MFR to SFO?
The cheapest flights from MFR to SFO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO)?
Board a direct flight with United Airlines and fly straight from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO).
What is the cheapest airline that flies from MFR to SFO?
With tickets starting at $214 for a one-way journey from MFR to SFO, United is currently the cheapest carrier for this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MFR on July 19 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO)?
Every day, an average of 2 nonstop flights take off from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO). Select the departure date that best fits your schedule.
What are the most popular departure times for flights from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO)?
Flights between MFR and SFO are busiest at 1 PM. If you’d like a quieter trip and potentially cheaper tickets, choose a departure outside the usual busy windows.
What day of the week has the most flights from MFR to SFO?
Friday has the most flights from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO). Consider taking off on this day and you’ll have a greater chance of finding a departure that fits your itinerary.
What is the earliest flight from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO)?
Catch the earliest flight at around 6:00AM UTC-8, departing from Rogue Valley Intl. Airport (MFR). You’ll be flying for around 1h 34m, landing at San Francisco Intl. Airport (SFO) at approximately 7:34AM UTC-8.
How long does it take to fly from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO)?
Flights from MFR to SFO have an average travel time of 1 hour and 36 minutes. The distance between these two airports is 330 mi.
What airline has the least delays from MFR to SFO?
Consider booking with United Airlines if you’d like to fly straight from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO) without any holdups. This carrier has the best track record for punctuality, with an on-time score of 86%. Want real-time updates? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO)?
To avoid possible delays on the Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO) route, travel before 3 PM. Flights after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for San Francisco from Rogue Valley Intl. Airport (MFR)?
If you’re boarding a direct flight from Rogue Valley Intl. Airport (MFR) to San Francisco, San Francisco Intl. Airport (SFO) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO) last-minute?
Last-minute bookings from MFR to SFO are typically more expensive. For the lowest rates, start searching for flights early. That being said, if you’re flexible with your travel plans, you may land a cheap ticket right before you leave.
Is it cheaper to book a MFR to SFO flight and hotel package?
Booking a MFR to SFO flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Pick from our wide range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO)?
If you reserved your MFR to SFO flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

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*Available to One Key members.