$100 Cheap Flights from Harrisburg (MDT) to Greenville (GSP)

View $100 flight on Fri, May 30, 2025Opens in a new window

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.

Cheap Flights from Harrisburg to Greenville (MDT-GSP)

Prices were available within the past 7 days and start at $100 for one-way flights and $199 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, May 28 - Fri, May 30
MDT
Harrisburg
GSP
Greenville
$199 Roundtrip, just found
$199
Roundtrip
just found
Select Delta flight, departing Wed, May 28 from Harrisburg to Greenville, returning Fri, May 30, priced at $199 just found
American Airlines
Fri, May 30 - Tue, Jun 3
MDT
Harrisburg
GSP
Greenville
$214 Roundtrip, found 1 day ago
$214
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 30 from Harrisburg to Greenville, returning Tue, Jun 3, priced at $214 found 1 day ago
Delta
Tue, Jul 1 - Fri, Jul 4
MDT
Harrisburg
GSP
Greenville
$217 Roundtrip, found 4 days ago
$217
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Jul 1 from Harrisburg to Greenville, returning Fri, Jul 4, priced at $217 found 4 days ago
Delta
Sun, May 11 - Wed, May 28
MDT
Harrisburg
GSP
Greenville
$219 Roundtrip, found 23 hours ago
$219
Roundtrip
found 23 hours ago
Select Delta flight, departing Sun, May 11 from Harrisburg to Greenville, returning Wed, May 28, priced at $219 found 23 hours ago
Delta
Sat, Jul 5 - Thu, Jul 10
MDT
Harrisburg
GSP
Greenville
$223 Roundtrip, found 2 days ago
$223
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Jul 5 from Harrisburg to Greenville, returning Thu, Jul 10, priced at $223 found 2 days ago
United
Thu, Jul 3 - Mon, Jul 7
MDT
Harrisburg
GSP
Greenville
$229 Roundtrip, just found
$229
Roundtrip
just found
Select United flight, departing Thu, Jul 3 from Harrisburg to Greenville, returning Mon, Jul 7, priced at $229 just found
Delta
Tue, May 6 - Tue, May 20
MDT
Harrisburg
GSP
Greenville
$234 Roundtrip, found 23 hours ago
$234
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, May 6 from Harrisburg to Greenville, returning Tue, May 20, priced at $234 found 23 hours ago
Delta
Mon, Jun 30 - Fri, Jul 11
MDT
Harrisburg
GSP
Greenville
$234 Roundtrip, found 23 hours ago
$234
Roundtrip
found 23 hours ago
Select Delta flight, departing Mon, Jun 30 from Harrisburg to Greenville, returning Fri, Jul 11, priced at $234 found 23 hours ago
Delta
Tue, May 6 - Sat, May 17
MDT
Harrisburg
GSP
Greenville
$239 Roundtrip, found 23 hours ago
$239
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, May 6 from Harrisburg to Greenville, returning Sat, May 17, priced at $239 found 23 hours ago
Delta
Wed, May 28 - Sat, Jun 7
MDT
Harrisburg
GSP
Greenville
$244 Roundtrip, just found
$244
Roundtrip
just found
Select Delta flight, departing Wed, May 28 from Harrisburg to Greenville, returning Sat, Jun 7, priced at $244 just found
Flights from Harrisburg (MDT) to Greenville (GSP)
Origin airport
Harrisburg Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$198
Distance
472 mi

Harrisburg to Greenville Flights

The cheapest times to fly from Harrisburg to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Harrisburg to Greenville are during the month of May. You can find some of the cheapest flights from Harrisburg to Greenville with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Harrisburg to Greenville

Sunday is one of the best days to book for cheap flights from Harrisburg to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Harrisburg to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Harrisburg to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Harrisburg to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Harrisburg to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Harrisburg Intl. Airport (MDT) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Discover the latest flight deals from MDT to GSP by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MDT to GSP?
The cheapest flights from MDT to GSP are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MDT to GSP?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from MDT to GSP. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Harrisburg Intl. Airport (MDT) to Greenville-Spartanburg Intl. Airport (GSP)?
You’ll have to hop on a flight with a layover when traveling from Harrisburg Intl. Airport (MDT) to Greenville-Spartanburg Intl. Airport (GSP). Direct flights don’t operate daily on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from MDT to GSP?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Harrisburg Intl. Airport (MDT) to Greenville-Spartanburg Intl. Airport (GSP)?
Select a flight from Harrisburg Intl. Airport (MDT) to Greenville-Spartanburg Intl. Airport (GSP) that takes off before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Harrisburg Intl. Airport (MDT) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Holding off until just before your departure to book a flight from MDT to GSP often results in higher prices. While you might find some last-minute discounts, there’s no guarantee. Keep your travel plans flexible to boost your chances of getting a bargain.
Is it cheaper to book a MDT to GSP flight and hotel package?
Compared with arranging flights and hotels separately, booking a MDT to GSP flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one place will take the stress out of travel planning. Simply pick your flights and choose from our extensive range of stays, then tailor your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Harrisburg Intl. Airport (MDT) to Greenville-Spartanburg Intl. Airport (GSP)?
Usually, it’s possible to cancel or reschedule your MDT to GSP flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline’s policies in your itinerary to see what changes are allowed and if any costs are involved. You’ll also find more details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.