$179 Cheap Flights from La Crosse (LSE) to Chicago (ORD)

View $179 flight on Fri, Jun 6, 2025Opens in a new window

Featured airlines

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.

Cheap Flights from La Crosse to Chicago (LSE-ORD)

Prices were available within the past 7 days and start at $179 for one-way flights and $327 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Jul 5 - Tue, Jul 8
LSE
La Crosse
ORD
Chicago
$327 Roundtrip, found 13 hours ago
$327
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, Jul 5 from La Crosse to Chicago, returning Tue, Jul 8, priced at $327 found 13 hours ago
American Airlines
Fri, Jul 25 - Sat, Jul 26
LSE
La Crosse
ORD
Chicago
$342 Roundtrip, found 1 day ago
$342
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Jul 25 from La Crosse to Chicago, returning Sat, Jul 26, priced at $342 found 1 day ago
American Airlines
Fri, Sep 26 - Sun, Sep 28
LSE
La Crosse
ORD
Chicago
$357 Roundtrip, found 1 day ago
$357
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 26 from La Crosse to Chicago, returning Sun, Sep 28, priced at $357 found 1 day ago
American Airlines
Tue, May 20 - Sat, May 24
LSE
La Crosse
ORD
Chicago
$366 Roundtrip, found 3 days ago
$366
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, May 20 from La Crosse to Chicago, returning Sat, May 24, priced at $366 found 3 days ago
American Airlines
Fri, Jul 25 - Sat, Jul 26
LSE
La Crosse
ORD
Chicago
$381 Roundtrip, found 1 day ago
$381
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Jul 25 from La Crosse to Chicago, returning Sat, Jul 26, priced at $381 found 1 day ago
American Airlines
Sat, Jul 5 - Tue, Jul 8
LSE
La Crosse
ORD
Chicago
$387 Roundtrip, found 13 hours ago
$387
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, Jul 5 from La Crosse to Chicago, returning Tue, Jul 8, priced at $387 found 13 hours ago
American Airlines
Tue, Jul 29 - Fri, Aug 15
LSE
La Crosse
ORD
Chicago
$402 Roundtrip, found 18 hours ago
$402
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Jul 29 from La Crosse to Chicago, returning Fri, Aug 15, priced at $402 found 18 hours ago
American Airlines
Sat, May 3 - Sat, May 10
LSE
La Crosse
ORD
Chicago
$405 Roundtrip, found 5 days ago
$405
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, May 3 from La Crosse to Chicago, returning Sat, May 10, priced at $405 found 5 days ago
American Airlines
Wed, Oct 1 - Wed, Oct 8
LSE
La Crosse
ORD
Chicago
$406 Roundtrip, found 1 day ago
$406
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Oct 1 from La Crosse to Chicago, returning Wed, Oct 8, priced at $406 found 1 day ago
American Airlines
Mon, Aug 18 - Sat, Aug 30
LSE
La Crosse
ORD
Chicago
$411 Roundtrip, found 18 hours ago
$411
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Mon, Aug 18 from La Crosse to Chicago, returning Sat, Aug 30, priced at $411 found 18 hours ago

Frequently asked questions

How much does a flight from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD) cost?
You can score cheap return flights from La Crosse Municipal Airport (LSE) to O’Hare Intl. Airport (ORD) starting from $327. Reserve your seat and get ready for takeoff. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a American Airlines flight leaving LSE on May 20 2025 and touching down at ORD. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from LSE to ORD?
The cheapest flights from LSE to ORD are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD)?
You can fly directly from La Crosse Municipal Airport (LSE) to O’Hare Intl. Airport (ORD) on an American Airlines flight.
What is the cheapest airline that flies from LSE to ORD?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from LSE to ORD. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD)?
With an average of 2 direct flights departing from La Crosse Municipal Airport (LSE) to O’Hare Intl. Airport (ORD) daily, you’ll be cruising above the clouds before you know it.
What are the most popular departure times for flights from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD)?
More passengers fly between LSE and ORD at 5 PM than at any other time. Rather skip the crowds? Try choosing a quieter departure window and you’re likely to save on your fare as well.
What day of the week has the most flights from LSE to ORD?
Friday has the most flights from La Crosse Municipal Airport (LSE) to O’Hare Intl. Airport (ORD). Consider leaving on this day and you’ll have a greater chance of finding a departure that fits your schedule.
What is the earliest flight from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD)?
The first flight of the day leaving from La Crosse Municipal Airport (LSE) is at around 6:00AM UTC-6. Board this flight and you’ll arrive at O’Hare Intl. Airport (ORD) at approximately 7:24AM UTC-6. The total travel time is 1h 24m.
How long does it take to fly from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD)?
Flights from LSE to ORD have an average travel time of 1 hour and 20 minutes. The total distance between the two airports is 210 mi.
What airline has the least delays from LSE to ORD?
American Airlines has the best performance for on-time direct flights from La Crosse Municipal Airport (LSE) to O’Hare Intl. Airport (ORD), with an on-time rating of 85%. Use the Expedia App to check your flight schedule before you jet off and receive notifications about any changes.
What is the best time to fly from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD)?
To avoid possible delays on the La Crosse Municipal Airport (LSE) to O’Hare Intl. Airport (ORD) route, travel before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Chicago from La Crosse Municipal Airport (LSE)?
O’Hare Intl. Airport (ORD) is the only airport in Chicago with direct flights from La Crosse Municipal Airport (LSE). Explore your options and find cheap fares on Expedia.
Is it cheaper to buy a plane ticket from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD) last-minute?
Last-minute fares from LSE to ORD are usually more expensive. To lock in the lowest prices, start searching for flights early. That being said, if you’re flexible with your travel plans, it’s possible to score a cheap fare just before your departure.
Is it cheaper to book a LSE to ORD flight and hotel package?
You’ll generally save money by booking a LSE to ORD flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it’s simple to manage everything in one place. Once you’ve chosen your preferred flights and accommodations, consider other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from La Crosse Municipal Airport (LSE) to O'Hare Intl. Airport (ORD)?
In most instances, you’re able to cancel or reschedule your LSE to ORD flight. However, there may be additional fees, especially if you booked over 24 hours ago. Check your itinerary for the airline’s fees and rules on flight changes, or if you need further details, visit our Customer Service portal.
*Available to One Key members.