$118 Cheap Flights from Istanbul (IST) to Madrid (MAD)

View $118 flight on Mon, Dec 15, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Istanbul to Madrid (IST-MAD)

Prices were available within the past 7 days and start at $118 for one-way flights and $254 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aegean
Sun, Feb 1 - Sat, Feb 14
IST
Istanbul
MAD
Madrid
$254 Roundtrip, found 6 days ago
$254
Roundtrip
found 6 days ago
Select Aegean flight, departing Sun, Feb 1 from Istanbul to Madrid, returning Sat, Feb 14, priced at $254 found 6 days ago
Aegean
Thu, Nov 20 - Wed, Nov 26
IST
Istanbul
MAD
Madrid
$254 Roundtrip, found 5 days ago
$254
Roundtrip
found 5 days ago
Select Aegean flight, departing Thu, Nov 20 from Istanbul to Madrid, returning Wed, Nov 26, priced at $254 found 5 days ago
Pegasus Airlines
Sun, Mar 1 - Wed, Mar 11
SAW
Istanbul
MAD
Madrid
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Select Pegasus Airlines flight, departing Sun, Mar 1 from Istanbul to Madrid, returning Wed, Mar 11, priced at $257 found 1 day ago
Air Serbia
Tue, May 20 - Fri, May 23
IST
Istanbul
MAD
Madrid
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Select Air Serbia flight, departing Tue, May 20 from Istanbul to Madrid, returning Fri, May 23, priced at $257 found 1 day ago
Air Serbia
Tue, May 27 - Wed, Jun 18
IST
Istanbul
MAD
Madrid
$258 Roundtrip, found 1 hour ago
$258
Roundtrip
found 1 hour ago
Select Air Serbia flight, departing Tue, May 27 from Istanbul to Madrid, returning Wed, Jun 18, priced at $258 found 1 hour ago
Air Europa
Fri, Nov 21 - Tue, Nov 25
IST
Istanbul
MAD
Madrid
$262 Roundtrip, found 2 days ago
$262
Roundtrip
found 2 days ago
Select Air Europa flight, departing Fri, Nov 21 from Istanbul to Madrid, returning Tue, Nov 25, priced at $262 found 2 days ago
Aegean
Mon, Nov 3 - Thu, Nov 20
IST
Istanbul
MAD
Madrid
$267 Roundtrip, found 1 day ago
$267
Roundtrip
found 1 day ago
Select Aegean flight, departing Mon, Nov 3 from Istanbul to Madrid, returning Thu, Nov 20, priced at $267 found 1 day ago
Air Europa
Fri, Nov 21 - Tue, Nov 25
IST
Istanbul
MAD
Madrid
$267 Roundtrip, found 2 days ago
$267
Roundtrip
found 2 days ago
Select Air Europa flight, departing Fri, Nov 21 from Istanbul to Madrid, returning Tue, Nov 25, priced at $267 found 2 days ago
Air Serbia
Fri, Nov 21 - Tue, Nov 25
IST
Istanbul
MAD
Madrid
$271 Roundtrip, found 2 days ago
$271
Roundtrip
found 2 days ago
Select Air Serbia flight, departing Fri, Nov 21 from Istanbul to Madrid, returning Tue, Nov 25, priced at $271 found 2 days ago
Lufthansa
Tue, Jun 3 - Sat, Jun 7
IST
Istanbul
MAD
Madrid
$277 Roundtrip, found 1 day ago
$277
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Tue, Jun 3 from Istanbul to Madrid, returning Sat, Jun 7, priced at $277 found 1 day ago
Flights from Istanbul (IST) to Madrid (MAD)
Origin airport
Istanbul
Destination airport
Adolfo Suárez Madrid-Barajas
Airlines serving
Aegean, Air Baltic, Air Europa, Air France, Air Serbia, British Airways, ITA Airways, KLM, KM Malta Airlines, LOT-Polish Airlines, Lufthansa, TAP Portugal, Tarom-Romanian Air Transport, Turkish Airlines
Roundtrip price
$253
Distance
1679 mi

Istanbul to Madrid Flights

The cheapest times to fly from Istanbul to Madrid

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Istanbul to Madrid are during the month of February. You can find some of the cheapest flights from Istanbul to Madrid with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Istanbul to Madrid

Sunday is one of the best days to book for cheap flights from Istanbul to Madrid: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Istanbul to Madrid

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Istanbul to Madrid in 2025. You can also book with separate airlines for your outbound and return journeys, from $118 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Istanbul to Madrid flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Istanbul to Madrid airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD) cost?
Grab cheap return tickets starting at $299 from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Air Europa flight leaving IST on May 16 2025 and touching down at MAD. The price was last updated on April 23 2025 and has not changed since.
What is the cheapest month to fly from IST to MAD?
The cheapest flights from IST to MAD are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
There aren’t any direct flights from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD). However, you can find other airports that offer nonstop flights. Begin your journey at Ataturk Intl. Airport (IST) and fly straight to Madrid without a layover.
What is the cheapest airline that flies from IST to MAD?
Currently, the cheapest carrier offering one-way flights from IST to MAD is Air Europa. You can jet off on this route from $197. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from IST on June 18 2025. Prices were last updated on April 23 2025 and have not changed since.
How many flights per day from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
You’ll need to book a flight with a layover when traveling from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from IST to MAD?
You’ll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from IST to MAD?
Consider booking with Turkish Airlines if you’d like to fly straight from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD) without any holdups. This carrier has the strongest track record for punctuality, with an on-time performance of 90%. Want to get notified of any changes? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
To land at Adolfo Suarez Madrid-Barajas Airport (MAD) without delays, pick a flight that takes off from Istanbul (IST) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD) last-minute?
Waiting until just before your trip to book a ticket from IST to MAD generally means paying more. While it’s possible to find some last-minute discounts, they’re not always guaranteed. Allow some flexibility in your schedule for the best chance of snagging a bargain.
Is it cheaper to book an IST to MAD flight and hotel package?
Compared with arranging hotels and flights separately, booking an IST to MAD flight and hotel package with Expedia could lead to significant savings. What’s more, managing everything in one place will take the hassle out of travel planning. Simply pick your flights and choose from our wide range of stays, then tailor your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Istanbul (IST) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
If you reserved your IST to MAD flight in the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more information.

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*Available to One Key members.