$129 Cheap Flights from Greenville (GSP) to St. Louis (STL)

View $129 flight on Fri, Jul 4, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Greenville to St. Louis (GSP-STL)

Prices were available within the past 7 days and start at $129 for one-way flights and $257 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Wed, May 28 - Tue, Jun 3
GSP
Greenville
STL
St. Louis
$257 Roundtrip, found 2 days ago
$257
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Wed, May 28 from Greenville to St. Louis, returning Tue, Jun 3, priced at $257 found 2 days ago
American Airlines
Tue, May 20 - Sun, May 25
GSP
Greenville
STL
St. Louis
$257 Roundtrip, found 23 hours ago
$257
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Tue, May 20 from Greenville to St. Louis, returning Sun, May 25, priced at $257 found 23 hours ago
Delta
Tue, Jun 10 - Tue, Jul 1
GSP
Greenville
STL
St. Louis
$257 Roundtrip, found 2 hours ago
$257
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Jun 10 from Greenville to St. Louis, returning Tue, Jul 1, priced at $257 found 2 hours ago
Delta
Tue, May 20 - Sun, May 25
GSP
Greenville
STL
St. Louis
$259 Roundtrip, found 23 hours ago
$259
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, May 20 from Greenville to St. Louis, returning Sun, May 25, priced at $259 found 23 hours ago
Delta
Tue, Jul 1 - Fri, Jul 4
GSP
Greenville
STL
St. Louis
$261 Roundtrip, found 3 days ago
$261
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Jul 1 from Greenville to St. Louis, returning Fri, Jul 4, priced at $261 found 3 days ago
Southwest Airlines
Tue, May 20 - Sun, May 25
GSP
Greenville
STL
St. Louis
$262 Roundtrip, found 23 hours ago
$262
Roundtrip
found 23 hours ago
Select Southwest Airlines flight, departing Tue, May 20 from Greenville to St. Louis, returning Sun, May 25, priced at $262 found 23 hours ago
American Airlines
Wed, Jun 11 - Wed, Jun 18
GSP
Greenville
STL
St. Louis
$266 Roundtrip, found 8 hours ago
$266
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jun 11 from Greenville to St. Louis, returning Wed, Jun 18, priced at $266 found 8 hours ago
Southwest Airlines
Thu, Sep 4 - Sun, Sep 7
GSP
Greenville
STL
St. Louis
$272 Roundtrip, just found
$272
Roundtrip
just found
Select Southwest Airlines flight, departing Thu, Sep 4 from Greenville to St. Louis, returning Sun, Sep 7, priced at $272 just found
Delta
Thu, May 22 - Sun, May 25
GSP
Greenville
STL
St. Louis
$276 Roundtrip, found 4 hours ago
$276
Roundtrip
found 4 hours ago
Select Delta flight, departing Thu, May 22 from Greenville to St. Louis, returning Sun, May 25, priced at $276 found 4 hours ago
United
Tue, Jul 1 - Fri, Jul 4
GSP
Greenville
STL
St. Louis
$286 Roundtrip, found 3 days ago
$286
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jul 1 from Greenville to St. Louis, returning Fri, Jul 4, priced at $286 found 3 days ago

Frequently asked questions

How much does a flight from Greenville-Spartanburg Intl. Airport (GSP) to Lambert-St. Louis Intl. Airport (STL) cost?
Discover the latest flight deals from GSP to STL by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from GSP to STL?
The cheapest flights from GSP to STL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from GSP to STL?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from GSP to STL. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Greenville-Spartanburg Intl. Airport (GSP) to Lambert-St. Louis Intl. Airport (STL)?
Direct flights from Greenville-Spartanburg Intl. Airport (GSP) to Lambert-St. Louis Intl. Airport (STL) aren’t available daily, so you’ll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and choose either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from GSP to STL?
You’ll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Greenville-Spartanburg Intl. Airport (GSP) to Lambert-St. Louis Intl. Airport (STL)?
To avoid potential delays on the Greenville-Spartanburg Intl. Airport (GSP) to Lambert-St. Louis Intl. Airport (STL) route, travel before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Greenville-Spartanburg Intl. Airport (GSP) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your ticket from GSP to STL right before your journey is typically more expensive. However, if there’s some wiggle room with your travel dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a GSP to STL flight and hotel package?
Compared with arranging flights and hotels separately, booking a GSP to STL flight and hotel package with Expedia could result in significant savings. What’s more, having everything in one convenient place will take the stress out of travel planning. Simply pick your flights and choose from our extensive range of hotels, then personalize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Greenville-Spartanburg Intl. Airport (GSP) to Lambert-St. Louis Intl. Airport (STL)?
It’s usually possible to reschedule or cancel your GSP to STL flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline’s policies in your itinerary to see what changes are allowed and whether any costs are involved. You’ll also find more information on our Customer Service portal.
*Available to One Key members.