$100 Cheap Flights from Sioux Falls (FSD) to St. Louis (STL)

View $100 flight on Tue, Jul 1, 2025Opens in a new window

Popular airlines from Sioux Falls Regional Airport (FSD) to St. Louis Lambert Intl. Airport (STL)

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Find available prices by choosing your travel dates.

Cheap Flights from Sioux Falls to St. Louis (FSD-STL)

Prices were available within the past 7 days and start at $100 for one-way flights and $199 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Jul 1 - Sat, Jul 5
FSD
Sioux Falls
STL
St. Louis
$199 Roundtrip, found 1 day ago
$199
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jul 1 from Sioux Falls to St. Louis, returning Sat, Jul 5, priced at $199 found 1 day ago
Frontier Airlines
Fri, May 9 - Sat, May 24
FSD
Sioux Falls
STL
St. Louis
$210 Roundtrip, just found
$210
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, May 9 from Sioux Falls to St. Louis, returning Sat, May 24, priced at $210 just found
Delta
Sat, May 24 - Fri, Jun 13
FSD
Sioux Falls
STL
St. Louis
$214 Roundtrip, just found
$214
Roundtrip
just found
Select Delta flight, departing Sat, May 24 from Sioux Falls to St. Louis, returning Fri, Jun 13, priced at $214 just found
Delta
Sat, May 24 - Wed, May 28
FSD
Sioux Falls
STL
St. Louis
$217 Roundtrip, found 3 days ago
$217
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, May 24 from Sioux Falls to St. Louis, returning Wed, May 28, priced at $217 found 3 days ago
Frontier Airlines
Fri, May 2 - Wed, May 21
FSD
Sioux Falls
STL
St. Louis
$218 Roundtrip, just found
$218
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, May 2 from Sioux Falls to St. Louis, returning Wed, May 21, priced at $218 just found
Frontier Airlines
Sun, Jun 1 - Wed, Jun 4
FSD
Sioux Falls
STL
St. Louis
$220 Roundtrip, found 1 day ago
$220
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Jun 1 from Sioux Falls to St. Louis, returning Wed, Jun 4, priced at $220 found 1 day ago
Delta
Mon, May 19 - Wed, May 28
FSD
Sioux Falls
STL
St. Louis
$223 Roundtrip, found 3 days ago
$223
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, May 19 from Sioux Falls to St. Louis, returning Wed, May 28, priced at $223 found 3 days ago
American Airlines
Sat, May 17 - Sat, May 24
FSD
Sioux Falls
STL
St. Louis
$225 Roundtrip, found 1 day ago
$225
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, May 17 from Sioux Falls to St. Louis, returning Sat, May 24, priced at $225 found 1 day ago
United
Sat, May 17 - Sat, May 24
FSD
Sioux Falls
STL
St. Louis
$225 Roundtrip, found 1 day ago
$225
Roundtrip
found 1 day ago
Select United flight, departing Sat, May 17 from Sioux Falls to St. Louis, returning Sat, May 24, priced at $225 found 1 day ago
Delta
Sat, May 17 - Sat, May 24
FSD
Sioux Falls
STL
St. Louis
$228 Roundtrip, found 1 day ago
$228
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, May 17 from Sioux Falls to St. Louis, returning Sat, May 24, priced at $228 found 1 day ago
Flights from Sioux Falls (FSD) to St. Louis (STL)
Origin airport
Sioux Falls Regional
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$198
Distance
470 mi

Sioux Falls to St. Louis Flights

The cheapest times to fly from Sioux Falls to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sioux Falls to St. Louis are during the month of July. You can find some of the cheapest flights from Sioux Falls to St. Louis with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Sioux Falls to St. Louis

Sunday is one of the best days to book for cheap flights from Sioux Falls to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Sioux Falls to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sioux Falls to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sioux Falls to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sioux Falls to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL) cost?
Discover the latest flight deals from FSD to STL by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from FSD to STL?
The cheapest flights from FSD to STL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from FSD to STL?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from FSD to STL. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL)?
There are no daily nonstop flights departing from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL). But you can opt for flights with layovers. Filter your search on Expedia to include one or more stops, and you’ll be soaring above the clouds in no time.
What day of the week has the most flights from FSD to STL?
Generally you’ll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* But this can change based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL)?
Book a flight from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL) that takes off before 3 PM to reduce the risk of cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your flight from FSD to STL right before your getaway is typically more expensive. But if you’re flexible with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a FSD to STL flight and hotel package?
You’ll generally save money by securing a FSD to STL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it’s easy to manage everything in one place. Once you’ve selected your ideal accommodations and flights, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL)?
Generally, it’s possible to cancel or reschedule your FSD to STL flight. However, if it’s been more than 24 hours since booking, additional charges may apply. Refer to your airline’s policies in your itinerary to see what changes are allowed and whether any costs are involved. You’ll also find more information on our Customer Service portal.

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*Available to One Key members.