$100 Cheap Flights from Key West (EYW) to Roanoke (ROA)

View $100 flight on Fri, May 30, 2025Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)

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Find available prices by choosing your travel dates.

Cheap Flights from Key West to Roanoke (EYW-ROA)

Prices were available within the past 7 days and start at $100 for one-way flights and $233 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, May 29 - Tue, Jun 17
EYW
Key West
ROA
Roanoke
$233 Roundtrip, found 4 days ago
$233
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, May 29 from Key West to Roanoke, returning Tue, Jun 17, priced at $233 found 4 days ago
American Airlines
Thu, Jun 5 - Tue, Jun 10
EYW
Key West
ROA
Roanoke
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jun 5 from Key West to Roanoke, returning Tue, Jun 10, priced at $249 found 1 day ago
Delta
Tue, May 13 - Sun, May 25
EYW
Key West
ROA
Roanoke
$263 Roundtrip, found 4 days ago
$263
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, May 13 from Key West to Roanoke, returning Sun, May 25, priced at $263 found 4 days ago
Delta
Tue, Jun 3 - Wed, Jun 11
EYW
Key West
ROA
Roanoke
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 3 from Key West to Roanoke, returning Wed, Jun 11, priced at $279 found 1 day ago
Delta
Tue, Apr 29 - Tue, May 6
EYW
Key West
ROA
Roanoke
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 29 from Key West to Roanoke, returning Tue, May 6, priced at $284 found 1 day ago
American Airlines
Thu, May 29 - Sun, Jun 15
EYW
Key West
ROA
Roanoke
$294 Roundtrip, found 4 days ago
$294
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, May 29 from Key West to Roanoke, returning Sun, Jun 15, priced at $294 found 4 days ago
Delta
Fri, Jun 13 - Tue, Jul 1
EYW
Key West
ROA
Roanoke
$298 Roundtrip, found 4 days ago
$298
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Jun 13 from Key West to Roanoke, returning Tue, Jul 1, priced at $298 found 4 days ago
American Airlines
Wed, May 28 - Wed, Jun 11
EYW
Key West
ROA
Roanoke
$299 Roundtrip, found 4 days ago
$299
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, May 28 from Key West to Roanoke, returning Wed, Jun 11, priced at $299 found 4 days ago
Delta
Tue, Apr 29 - Sat, May 3
EYW
Key West
ROA
Roanoke
$309 Roundtrip, found 1 day ago
$309
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Apr 29 from Key West to Roanoke, returning Sat, May 3, priced at $309 found 1 day ago
United
Fri, Jun 27 - Sat, Jul 12
EYW
Key West
ROA
Roanoke
$386 Roundtrip, found 4 days ago
$386
Roundtrip
found 4 days ago
Select United flight, departing Fri, Jun 27 from Key West to Roanoke, returning Sat, Jul 12, priced at $386 found 4 days ago
Flights from Key West (EYW) to Roanoke (ROA)
Origin airport
Key West Intl.
Destination airport
Roanoke Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$232
Distance
888 mi

Key West to Roanoke Flights

The cheapest times to fly from Key West to Roanoke

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to Roanoke are during the month of May. You can find some of the cheapest flights from Key West to Roanoke with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Key West to Roanoke

Sunday is one of the best days to book for cheap flights from Key West to Roanoke: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Key West to Roanoke

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to Roanoke in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to Roanoke flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to Roanoke airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA) cost?
Discover the latest flight deals from EYW to ROA by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from EYW to ROA?
The cheapest flights from EYW to ROA are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from EYW to ROA?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from EYW to ROA. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)?
You’ll have to book a flight with a layover if you’re traveling from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA). Direct flights don’t operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from EYW to ROA?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a range of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)?
Opt for a flight from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA) that takes off before 3 PM to reduce the risk of cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA) last-minute?
Last-minute bookings from EYW to ROA are generally more expensive. To secure the best prices, start searching for flights well in advance. That said, if you can play around with your travel dates, you may find a cheap fare right before your journey.
Is it cheaper to book an EYW to ROA flight and hotel package?
You’ll typically save money by booking an EYW to ROA flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage it all in one convenient place. Once you’ve selected your ideal accommodations and flights, you can add extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)?
You can usually reschedule or cancel your EYW to ROA flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline’s policies in your itinerary to see what changes are possible and whether any costs are involved. You’ll also find more information on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.