$78 Cheap Flights from Key West (EYW) to New Orleans (MSY)

View $78 flight on Fri, Aug 8, 2025Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to Louis Armstrong New Orleans Intl. Airport (MSY)

Find available prices by choosing your travel dates.

Cheap Flights from Key West to New Orleans (EYW-MSY)

Prices were available within the past 7 days and start at $78 for one-way flights and $224 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, May 29 - Sun, Jun 15
EYW
Key West
MSY
New Orleans
$224 Roundtrip, found 5 days ago
$224
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, May 29 from Key West to New Orleans, returning Sun, Jun 15, priced at $224 found 5 days ago
American Airlines
Wed, May 21 - Wed, May 28
EYW
Key West
MSY
New Orleans
$225 Roundtrip, found 9 hours ago
$225
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Wed, May 21 from Key West to New Orleans, returning Wed, May 28, priced at $225 found 9 hours ago
Delta
Wed, May 21 - Wed, May 28
EYW
Key West
MSY
New Orleans
$228 Roundtrip, found 9 hours ago
$228
Roundtrip
found 9 hours ago
Select Delta flight, departing Wed, May 21 from Key West to New Orleans, returning Wed, May 28, priced at $228 found 9 hours ago
American Airlines
Thu, May 15 - Mon, May 19
EYW
Key West
MSY
New Orleans
$249 Roundtrip, found 6 hours ago
$249
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Thu, May 15 from Key West to New Orleans, returning Mon, May 19, priced at $249 found 6 hours ago
Delta
Tue, May 20 - Wed, May 21
EYW
Key West
MSY
New Orleans
$251 Roundtrip, found 2 days ago
$251
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, May 20 from Key West to New Orleans, returning Wed, May 21, priced at $251 found 2 days ago
American Airlines
Tue, Jun 17 - Sat, Jun 21
EYW
Key West
MSY
New Orleans
$253 Roundtrip, found 2 days ago
$253
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 17 from Key West to New Orleans, returning Sat, Jun 21, priced at $253 found 2 days ago
Delta
Thu, May 8 - Mon, May 12
EYW
Key West
MSY
New Orleans
$254 Roundtrip, found 3 days ago
$254
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, May 8 from Key West to New Orleans, returning Mon, May 12, priced at $254 found 3 days ago
Delta
Wed, Oct 1 - Sat, Oct 4
EYW
Key West
MSY
New Orleans
$255 Roundtrip, found 1 day ago
$255
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Oct 1 from Key West to New Orleans, returning Sat, Oct 4, priced at $255 found 1 day ago
United
Tue, Jun 17 - Sat, Jun 21
EYW
Key West
MSY
New Orleans
$288 Roundtrip, found 2 days ago
$288
Roundtrip
found 2 days ago
Select United flight, departing Tue, Jun 17 from Key West to New Orleans, returning Sat, Jun 21, priced at $288 found 2 days ago
Breeze Airways
Fri, Jun 13 - Mon, Jun 16
EYW
Key West
MSY
New Orleans
$307 Roundtrip, found 1 day ago
$307
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Fri, Jun 13 from Key West to New Orleans, returning Mon, Jun 16, priced at $307 found 1 day ago
Flights from Key West (EYW) to New Orleans (MSY)
Origin airport
Key West Intl.
Destination airport
Louis Armstrong New Orleans Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$223
Distance
642 mi

Key West to New Orleans Flights

The cheapest times to fly from Key West to New Orleans

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to New Orleans are during the month of May. You can find some of the cheapest flights from Key West to New Orleans with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Key West to New Orleans

Sunday is one of the best days to book for cheap flights from Key West to New Orleans: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Key West to New Orleans

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to New Orleans in 2025. You can also book with separate airlines for your outbound and return journeys, from $78 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to New Orleans flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to New Orleans airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to Louis Armstrong New Orleans Intl. Airport (MSY) cost?
Discover the latest flight deals from EYW to MSY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from EYW to MSY?
The cheapest flights from EYW to MSY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from EYW to MSY?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from EYW to MSY. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Key West Intl. Airport (EYW) to Louis Armstrong New Orleans Intl. Airport (MSY)?
Nonstop flights from Key West Intl. Airport (EYW) to Louis Armstrong New Orleans Intl. Airport (MSY) aren’t available daily, so you’ll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and choose either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from EYW to MSY?
You’ll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Key West Intl. Airport (EYW) to Louis Armstrong New Orleans Intl. Airport (MSY)?
Book a flight from Key West Intl. Airport (EYW) to Louis Armstrong New Orleans Intl. Airport (MSY) that takes off before 3 PM to reduce the likelihood of delays. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to Louis Armstrong New Orleans Intl. Airport (MSY) last-minute?
Holding off until just before your departure to book a flight from EYW to MSY generally means paying more. While you might find some last-minute deals, there’s no guarantee. Be flexible with your itinerary to maximize your chances of scoring a bargain.
Is it cheaper to book an EYW to MSY flight and hotel package?
Compared with arranging hotels and flights separately, booking an EYW to MSY flight and hotel package with Expedia could result in significant savings. What’s more, having everything in one place will take the hassle out of travel planning. Just secure your flights and choose from our extensive range of stays, then customize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to Louis Armstrong New Orleans Intl. Airport (MSY)?
Typically, you’re able to reschedule or cancel your EYW to MSY flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline’s fees and rules on flight changes, or if you’d like further details, head to our Customer Service portal.

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*Available to One Key members.