$79 Cheap Flights from Key West (EYW) to Charleston (CHS)

View $79 flight on Thu, Jul 3, 2025Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to Charleston Intl. Airport (CHS)

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Find available prices by choosing your travel dates.

Cheap Flights from Key West to Charleston (EYW-CHS)

Prices were available within the past 7 days and start at $79 for one-way flights and $301 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Breeze Airways
Thu, Jul 10 - Sun, Jul 13
EYW
Key West
CHS
Charleston
$301 Roundtrip, found 2 hours ago
$301
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Thu, Jul 10 from Key West to Charleston, returning Sun, Jul 13, priced at $301 found 2 hours ago
Breeze Airways
Thu, Jul 10 - Sun, Jul 13
EYW
Key West
CHS
Charleston
$306 Roundtrip, found 2 hours ago
$306
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Thu, Jul 10 from Key West to Charleston, returning Sun, Jul 13, priced at $306 found 2 hours ago
Breeze Airways
Thu, Jul 10 - Sun, Jul 13
EYW
Key West
CHS
Charleston
$319 Roundtrip, found 2 hours ago
$319
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Thu, Jul 10 from Key West to Charleston, returning Sun, Jul 13, priced at $319 found 2 hours ago
Breeze Airways
Thu, Jul 10 - Sun, Jul 13
EYW
Key West
CHS
Charleston
$324 Roundtrip, found 2 hours ago
$324
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Thu, Jul 10 from Key West to Charleston, returning Sun, Jul 13, priced at $324 found 2 hours ago
Breeze Airways
Thu, Jul 10 - Sun, Jul 13
EYW
Key West
CHS
Charleston
$329 Roundtrip, found 2 hours ago
$329
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Thu, Jul 10 from Key West to Charleston, returning Sun, Jul 13, priced at $329 found 2 hours ago
Breeze Airways
Thu, Jul 10 - Sun, Jul 13
EYW
Key West
CHS
Charleston
$334 Roundtrip, found 2 hours ago
$334
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Thu, Jul 10 from Key West to Charleston, returning Sun, Jul 13, priced at $334 found 2 hours ago
American Airlines
Sat, May 24 - Sat, May 31
EYW
Key West
CHS
Charleston
$337 Roundtrip, found 2 days ago
$337
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, May 24 from Key West to Charleston, returning Sat, May 31, priced at $337 found 2 days ago
Delta
Tue, Jul 22 - Sat, Jul 26
EYW
Key West
CHS
Charleston
$337 Roundtrip, found 2 days ago
$337
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jul 22 from Key West to Charleston, returning Sat, Jul 26, priced at $337 found 2 days ago
United
Sat, Jun 7 - Tue, Jun 10
EYW
Key West
CHS
Charleston
$373 Roundtrip, found 6 days ago
$373
Roundtrip
found 6 days ago
Select United flight, departing Sat, Jun 7 from Key West to Charleston, returning Tue, Jun 10, priced at $373 found 6 days ago
Silver Airways
Sat, Jun 7 - Wed, Jun 11
EYW
Key West
CHS
Charleston
$401 Roundtrip, found 1 day ago
$401
Roundtrip
found 1 day ago
Select Silver Airways flight, departing Sat, Jun 7 from Key West to Charleston, returning Wed, Jun 11, priced at $401 found 1 day ago
Flights from Key West (EYW) to Charleston (CHS)
Origin airport
Key West Intl.
Destination airport
Charleston Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, United
Roundtrip price
$300
Distance
584 mi

Key West to Charleston Flights

The cheapest times to fly from Key West to Charleston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to Charleston are during the month of July. You can find some of the cheapest flights from Key West to Charleston with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Key West to Charleston

Sunday is one of the best days to book for cheap flights from Key West to Charleston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Key West to Charleston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to Charleston in 2025. You can also book with separate airlines for your outbound and return journeys, from $79 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to Charleston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to Charleston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to Charleston Intl. Airport (CHS) cost?
Discover the latest flight deals from EYW to CHS by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from EYW to CHS?
The cheapest flights from EYW to CHS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from EYW to CHS?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from EYW to CHS. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Key West Intl. Airport (EYW) to Charleston Intl. Airport (CHS)?
You’ll need to take a flight with a layover if you’re traveling from Key West Intl. Airport (EYW) to Charleston Intl. Airport (CHS). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from EYW to CHS?
You’ll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Key West Intl. Airport (EYW) to Charleston Intl. Airport (CHS)?
To arrive at Charleston Intl. Airport (CHS) on time, select a flight that leaves from Key West Intl. Airport (EYW) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to Charleston Intl. Airport (CHS) last-minute?
Holding off until just before your trip to book a ticket from EYW to CHS often results in higher prices. While you might find some last-minute deals, there’s no guarantee. Allow some flexibility in your schedule to boost your chances of getting a bargain.
Is it cheaper to book an EYW to CHS flight and hotel package?
Securing an EYW to CHS flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our impressive range of accommodations and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to Charleston Intl. Airport (CHS)?
It’s usually possible to cancel or reschedule your EYW to CHS flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline’s policies in your itinerary to see what changes are possible and whether any costs are involved. You’ll also find more details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.