Cheap Flights from Panama City (ECP) to Columbia (COU)

Popular airlines from Northwest Florida Beaches Intl. Airport (ECP) to Columbia, MO (COU-Columbia Regional)

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Find available prices by choosing your travel dates.

Cheap Flights from Panama City to Columbia (ECP-COU)

Prices were available within the past 7 days and start at for one-way flights and $410 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
Flights from Panama City (ECP) to Columbia (COU)
Origin airport
Northwest Florida Beaches Intl.
Destination airport
Columbia Regional
Roundtrip price
$410
Distance
688 mi

Panama City to Columbia Flights

The cheapest times to fly from Panama City to Columbia

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Columbia are during the month of October. You can find some of the cheapest flights from Panama City to Columbia with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Panama City to Columbia

Sunday is one of the best days to book for cheap flights from Panama City to Columbia: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Panama City to Columbia

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Columbia in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Columbia flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Columbia airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

Is it cheaper to buy a plane ticket from Northwest Florida Beaches Intl. Airport (ECP) to COU last minute?
Being the spontaneous type is a terrific way to travel the globe, but it’s not always the best way to find a cheap fare. Think about booking your Northwest Florida Beaches Intl. Airport (ECP) to Columbia Regional Airport (COU) trip in advance instead of leaving it to the last minute. Based on flight pricing and demand studies in 2022, we have found that the best time to book domestic flights is between 28 – 35 days ahead of the departure date, and international flights three to four months in advance. We recommend saving that spontaneity for when you’re discovering Columbia Regional Airport (COU)!
What airports do you fly into for Columbia from Panama City?
Columbia Regional Airport (COU), Jefferson City Memorial Airport (JEF) and Versailles, MO (VRS-Roy Otten Memorial Airfield) are your options when jetting from Panama City to Columbia. Around 11 mi southeast of central Columbia, Columbia Regional Airport (COU) is the city’s main gateway. Keep in mind factors such as flight schedules and the distance to your hotel before choosing an airport. University of Missouri and Mizzou Arena are a couple of fantastic attractions to explore when you arrive at your destination.
Can I change the date of my flight from Northwest Florida Beaches Intl. Airport (ECP) to Columbia Regional Airport (COU)?
It’s a piece of cake to make amendments to your Northwest Florida Beaches Intl. Airport (ECP) to COU journey yourself. Just go to the Expedia Trips portal and select “change flight.” Search for new flights and secure the one that fits your new plans. You’ll see an estimate of flight change fees that may apply. You can also use our Customer Service portal to connect with our Virtual Agent and quickly get answers to your questions.

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