$147 Cheap Flights from Detroit (DTW) to Greenville (GSP)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
Find available prices by choosing your travel dates.

Cheap Flights from Detroit to Greenville (DTW-GSP)

Prices were available within the past 7 days and start at $147 for one-way flights and $291 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Southwest Airlines
American Airlines
American Airlines
United
Southwest Airlines
American Airlines
Delta
Southwest Airlines
American Airlines
Flights from Detroit (DTW) to Greenville (GSP)
Origin airport
Detroit Metropolitan Wayne County
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$291
Distance
510 mi

Detroit to Greenville Flights

The cheapest times to fly from Detroit to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Detroit to Greenville are during the month of August. You can find some of the cheapest flights from Detroit to Greenville with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Detroit to Greenville

Sunday is one of the best days to book for cheap flights from Detroit to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Detroit to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Detroit to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $147 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Detroit to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Detroit to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How long does it take to fly from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
Delta Air Lines operates a direct flight heading off from Metro Airport at 9:30PM and arriving at Greenville-Spartanburg Intl. Airport (GSP) at 11:10PM — a total flying time of 1 hour and 40 minutes. Pick the seat that’s perfect for you, bring something to keep you occupied and the time will zip by.
Is it cheaper to buy a plane ticket from Detroit Metro Airport to GSP last minute?
Being spontaneous is a rewarding way to see the world, but it’s not necessarily the best method to find a bargain flight. It’s better to book your DTW to Roger Milliken Field journey well in advance instead of leaving it until the last minute. Based on flight pricing and demand studies in 2022, we have found that the best time to book domestic flights is between 28 – 35 days ahead of the departure date, and international flights three to four months in advance. Leave all that spontaneity for when you’re exploring Roger Milliken Field!
What airports do you fly into for Greenville from Detroit?
From Detroit, you can reach Greenville through Greenville-Spartanburg Intl. Airport (GSP), Asheville Regional Airport (AVL) and Greenville, SC (GMU-Greenville Downtown). It’s a good idea to check which terminal is the right option for you before you make a decision. If you settle on Greenville-Spartanburg Intl. Airport (GSP), it’s around 11 mi east of the downtown area. Use the dough you save when booking your airfare with Expedia to check out the city’s popular attractions, such as Haywood Mall and Furman University.
What are the most popular departure times for flights from Metro Airport to Greenville-Spartanburg Intl. Airport (GSP)?
Between 12:00 PM - 1:00 PM is when you’ll find the most Delta Air Lines flights from Detroit Metro Airport to Greenville-Spartanburg Intl. Airport (GSP). Our recommendation? Book a flight that departs early. With air traffic yet to build up, your odds of boarding a delay-free flight are better.
Can I change the date of my flight from DTW to Roger Milliken Field?
You can easily make changes to your DTW to Roger Milliken Field flight via the Expedia Trips portal. Before you make any amendments, read the rules and conditions in your itinerary to find out what the carrier will allow you to do and if fees apply. Some airlines have a change fee per person, on top of any difference in ticket prices. However, if you booked in the last 24 hours, you may be able to cancel for free and book new flights. You can also take a look at our Customer Service portal for more useful advice and to connect with our Virtual Agent.

Explore a world of travel with Expedia

*Available to One Key members.