Cheap Flights from Des Moines (DSM) to St. Louis (SUS)

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Flights from Des Moines (DSM) to St. Louis (SUS)
Origin airport
Des Moines Intl.
Destination airport
Spirit of St. Louis
Distance
253 mi

Des Moines to St. Louis Flights

The cheapest times to fly from Des Moines to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to St. Louis are during the month of . You can find some of the cheapest flights from Des Moines to St. Louis with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Des Moines to St. Louis

Sunday is one of the best days to book for cheap flights from Des Moines to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Des Moines to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Spirit of St. Louis Airport (SUS) cost?
Discover the latest flight deals from DSM to SUS by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from DSM to SUS?
The cheapest flights from DSM to SUS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from DSM to SUS?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from DSM to SUS. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Spirit of St. Louis Airport (SUS)?
Nonstop flights from Des Moines Intl. Airport (DSM) to Spirit of St. Louis Airport (SUS) aren’t available daily, so you’ll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and click on either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from DSM to SUS?
Typically you’ll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Spirit of St. Louis Airport (SUS)?
Book a flight from Des Moines Intl. Airport (DSM) to Spirit of St. Louis Airport (SUS) that takes off before 3 PM to reduce the likelihood of delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for St. Louis from Des Moines Intl. Airport (DSM)?
Compare your flight options from Des Moines Intl. Airport (DSM) to Lambert-St. Louis Intl. Airport (STL). This is the only airport in St. Louis you can jet into if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Spirit of St. Louis Airport (SUS) last-minute?
Booking your flight from DSM to SUS right before your journey is generally more expensive. But if there’s some wiggle room with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a DSM to SUS flight and hotel package?
You’ll generally save money by booking a DSM to SUS flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s simple to manage it all in one place. After selecting your ideal flights and accommodations, consider adding extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Spirit of St. Louis Airport (SUS)?
If you booked your DSM to SUS flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

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*Available to One Key members.