$537 Cheap Flights from Des Moines (DSM) to Southampton (SOU)

Popular airlines from Des Moines International Airport (DSM) to Southampton (SOU)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
Find available prices by choosing your travel dates.

Cheap Flights from Des Moines to Southampton (DSM-SOU)

Prices were available within the past 7 days and start at $537 for one-way flights and $1,014 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Virgin Atlantic
KLM
Virgin Atlantic
Delta
KLM
KLM
Delta
KLM
Aer Lingus
American Airlines

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Southampton Airport (SOU) cost?
Discover the latest flight deals from DSM to SOU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from DSM to SOU?
The cheapest flights from DSM to SOU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from DSM to SOU?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from DSM to SOU. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Southampton Airport (SOU)?
Direct flights from Des Moines Intl. Airport (DSM) to Southampton Airport (SOU) aren’t available daily, so you’ll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and pick either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from DSM to SOU?
You’ll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Southampton Airport (SOU)?
Book a flight from Des Moines Intl. Airport (DSM) to Southampton Airport (SOU) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Southampton Airport (SOU) last-minute?
Waiting until just before your departure to book a flight from DSM to SOU often results in higher prices. Although you may find some last-minute discounts, there’s no guarantee. Keep your travel schedule open to boost your chances of getting a bargain.
Is it cheaper to book a DSM to SOU flight and hotel package?
Securing a DSM to SOU flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our impressive range of accommodations and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Southampton Airport (SOU)?
In most instances, you can modify or cancel your DSM to SOU flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline’s fees and policies on flight changes, or if you need more information, go to our Customer Service portal.
*Available to One Key members.