$104 Cheap Flights from Des Moines (DSM) to Philadelphia (PHL)

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Find available prices by choosing your travel dates.

Cheap Flights from Des Moines to Philadelphia (DSM-PHL)

Prices were available within the past 7 days and start at $104 for one-way flights and $204 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Frontier Airlines
United
United
Frontier Airlines
Delta
American Airlines
Delta
Delta
Southwest Airlines

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Philadelphia Intl. Airport (PHL) cost?
Discover the latest flight deals from DSM to PHL by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from DSM to PHL?
The cheapest flights from DSM to PHL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from DSM to PHL?
Right now, the cheapest airline operating one-way flights from DSM to PHL is American Airlines. You can book a seat on this route from $162. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from DSM on June 23 2025. Prices were last updated on April 22 2025 and have not changed since.
How many flights per day from Des Moines Intl. Airport (DSM) to Philadelphia Intl. Airport (PHL)?
You’ll have to book a flight with a layover when traveling from Des Moines Intl. Airport (DSM) to Philadelphia Intl. Airport (PHL). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from DSM to PHL?
Generally you’ll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* But this can change depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from DSM to PHL?
With 89% of flights generally arriving on time, American Airlines has the best on-time performance for nonstop flights from Des Moines Intl. Airport (DSM) to Philadelphia Intl. Airport (PHL). To keep track of your flight status and get notified about any changes, use the Expedia App.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Philadelphia Intl. Airport (PHL)?
Opt for a flight from Des Moines Intl. Airport (DSM) to Philadelphia Intl. Airport (PHL) that takes off before 3 PM to reduce the risk of delays and cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Philadelphia Intl. Airport (PHL) last-minute?
Last-minute fares from DSM to PHL are generally more expensive. To secure the lowest rates, start looking for flights well in advance. That being said, if your travel plans are flexible, you may find a cheap ticket just before your departure.
Is it cheaper to book a DSM to PHL flight and hotel package?
Compared with arranging hotels and flights separately, booking a DSM to PHL flight and hotel package with Expedia could lead to significant savings. What’s more, managing everything in one place will take the stress out of planning your trip. Just secure your flights and select from our extensive range of stays, then customize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Philadelphia Intl. Airport (PHL)?
In most instances, you can cancel or reschedule your DSM to PHL flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline’s fees and guidelines on flight changes, or if you need further details, go to our Customer Service portal.
*Available to One Key members.