$115 Cheap Flights from Des Moines (DSM) to Milwaukee (MKE)

View $115 flight on Tue, May 20, 2025Opens in a new window
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Cheap Flights from Des Moines to Milwaukee (DSM-MKE)

Prices were available within the past 7 days and start at $115 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jun 3 - Wed, Jun 4
DSM
Des Moines
MKE
Milwaukee
$229 Roundtrip, found 15 hours ago
$229
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Tue, Jun 3 from Des Moines to Milwaukee, returning Wed, Jun 4, priced at $229 found 15 hours ago
Delta
Tue, Jun 3 - Wed, Jun 4
DSM
Des Moines
MKE
Milwaukee
$229 Roundtrip, found 15 hours ago
$229
Roundtrip
found 15 hours ago
Select Delta flight, departing Tue, Jun 3 from Des Moines to Milwaukee, returning Wed, Jun 4, priced at $229 found 15 hours ago
United
Tue, Jun 3 - Wed, Jun 4
DSM
Des Moines
MKE
Milwaukee
$229 Roundtrip, found 15 hours ago
$229
Roundtrip
found 15 hours ago
Select United flight, departing Tue, Jun 3 from Des Moines to Milwaukee, returning Wed, Jun 4, priced at $229 found 15 hours ago
American Airlines
Tue, Jun 3 - Wed, Jun 4
DSM
Des Moines
MKE
Milwaukee
$232 Roundtrip, found 15 hours ago
$232
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Tue, Jun 3 from Des Moines to Milwaukee, returning Wed, Jun 4, priced at $232 found 15 hours ago
United
Tue, Jun 3 - Wed, Jun 4
DSM
Des Moines
MKE
Milwaukee
$239 Roundtrip, found 15 hours ago
$239
Roundtrip
found 15 hours ago
Select United flight, departing Tue, Jun 3 from Des Moines to Milwaukee, returning Wed, Jun 4, priced at $239 found 15 hours ago
Delta
Tue, Jul 1 - Tue, Jul 15
DSM
Des Moines
MKE
Milwaukee
$240 Roundtrip, found 9 hours ago
$240
Roundtrip
found 9 hours ago
Select Delta flight, departing Tue, Jul 1 from Des Moines to Milwaukee, returning Tue, Jul 15, priced at $240 found 9 hours ago
Delta
Tue, Jul 1 - Thu, Jul 17
DSM
Des Moines
MKE
Milwaukee
$242 Roundtrip, found 9 hours ago
$242
Roundtrip
found 9 hours ago
Select Delta flight, departing Tue, Jul 1 from Des Moines to Milwaukee, returning Thu, Jul 17, priced at $242 found 9 hours ago
United
Tue, Jun 3 - Wed, Jun 4
DSM
Des Moines
MKE
Milwaukee
$242 Roundtrip, found 15 hours ago
$242
Roundtrip
found 15 hours ago
Select United flight, departing Tue, Jun 3 from Des Moines to Milwaukee, returning Wed, Jun 4, priced at $242 found 15 hours ago
Delta
Fri, May 30 - Sat, Jun 7
DSM
Des Moines
MKE
Milwaukee
$244 Roundtrip, found 6 days ago
$244
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, May 30 from Des Moines to Milwaukee, returning Sat, Jun 7, priced at $244 found 6 days ago
Southwest Airlines
Tue, Jun 3 - Wed, Jun 4
DSM
Des Moines
MKE
Milwaukee
$245 Roundtrip, found 15 hours ago
$245
Roundtrip
found 15 hours ago
Select Southwest Airlines flight, departing Tue, Jun 3 from Des Moines to Milwaukee, returning Wed, Jun 4, priced at $245 found 15 hours ago
Flights from Des Moines (DSM) to Milwaukee (MKE)
Origin airport
Des Moines Intl.
Destination airport
General Mitchell Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$228
Distance
309 mi

Des Moines to Milwaukee Flights

The cheapest times to fly from Des Moines to Milwaukee

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Milwaukee are during the month of June. You can find some of the cheapest flights from Des Moines to Milwaukee with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Des Moines to Milwaukee

Sunday is one of the best days to book for cheap flights from Des Moines to Milwaukee: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Des Moines to Milwaukee

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Milwaukee in 2025. You can also book with separate airlines for your outbound and return journeys, from $115 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Milwaukee flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Milwaukee airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to General Mitchell Intl. Airport (MKE) cost?
Discover the latest flight deals from DSM to MKE by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from DSM to MKE?
The cheapest flights from DSM to MKE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from DSM to MKE?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from DSM to MKE. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to General Mitchell Intl. Airport (MKE)?
Direct flights from Des Moines Intl. Airport (DSM) to General Mitchell Intl. Airport (MKE) aren’t available daily, so you’ll have to take a flight with a layover. Explore your options with Expedia’s filter tool. Enter your travel details and click on either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from DSM to MKE?
You’ll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to General Mitchell Intl. Airport (MKE)?
Choose a flight from Des Moines Intl. Airport (DSM) to General Mitchell Intl. Airport (MKE) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to General Mitchell Intl. Airport (MKE) last-minute?
Booking your plane ticket from DSM to MKE just before your journey is generally more expensive. But if you’re flexible with your schedule, you could snag a cheap last-minute fare.
Is it cheaper to book a DSM to MKE flight and hotel package?
Compared with arranging hotels and flights separately, booking a DSM to MKE flight and hotel package with Expedia could lead to significant savings. What’s more, having everything in one easy place will take the stress out of travel planning. Simply secure your flights and choose from our extensive range of stays, then tailor your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to General Mitchell Intl. Airport (MKE)?
If you booked your DSM to MKE flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you’d like more information.

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*Available to One Key members.