$314 Cheap Flights from Denver (DEN) to La Crosse (LSE)

View $314 flight on Tue, May 20, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Denver to La Crosse (DEN-LSE)

Prices were available within the past 7 days and start at $314 for one-way flights and $444 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Sep 24 - Sat, Sep 27
DEN
Denver
LSE
La Crosse
$444 Roundtrip, found 3 days ago
$444
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Sep 24 from Denver to La Crosse, returning Sat, Sep 27, priced at $444 found 3 days ago
American Airlines
Wed, Sep 24 - Sat, Sep 27
DEN
Denver
LSE
La Crosse
$450 Roundtrip, found 3 days ago
$450
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Sep 24 from Denver to La Crosse, returning Sat, Sep 27, priced at $450 found 3 days ago
American Airlines
Wed, Sep 24 - Sat, Sep 27
DEN
Denver
LSE
La Crosse
$465 Roundtrip, found 5 days ago
$465
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 24 from Denver to La Crosse, returning Sat, Sep 27, priced at $465 found 5 days ago
American Airlines
Wed, Sep 24 - Sat, Sep 27
DEN
Denver
LSE
La Crosse
$466 Roundtrip, found 3 days ago
$466
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Sep 24 from Denver to La Crosse, returning Sat, Sep 27, priced at $466 found 3 days ago
American Airlines
Wed, Sep 24 - Sat, Sep 27
DEN
Denver
LSE
La Crosse
$470 Roundtrip, found 5 days ago
$470
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 24 from Denver to La Crosse, returning Sat, Sep 27, priced at $470 found 5 days ago
American Airlines
Mon, Jun 2 - Tue, Jun 24
DEN
Denver
LSE
La Crosse
$474 Roundtrip, found 3 days ago
$474
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jun 2 from Denver to La Crosse, returning Tue, Jun 24, priced at $474 found 3 days ago
American Airlines
Wed, May 14 - Wed, May 21
DEN
Denver
LSE
La Crosse
$476 Roundtrip, found 1 day ago
$476
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 14 from Denver to La Crosse, returning Wed, May 21, priced at $476 found 1 day ago
American Airlines
Mon, Jun 2 - Tue, Jun 24
DEN
Denver
LSE
La Crosse
$480 Roundtrip, found 3 days ago
$480
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jun 2 from Denver to La Crosse, returning Tue, Jun 24, priced at $480 found 3 days ago
American Airlines
Sat, May 3 - Sat, May 10
DEN
Denver
LSE
La Crosse
$482 Roundtrip, found 4 days ago
$482
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 3 from Denver to La Crosse, returning Sat, May 10, priced at $482 found 4 days ago
American Airlines
Wed, Sep 24 - Sat, Sep 27
DEN
Denver
LSE
La Crosse
$486 Roundtrip, found 5 days ago
$486
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 24 from Denver to La Crosse, returning Sat, Sep 27, priced at $486 found 5 days ago
Flights from Denver (DEN) to La Crosse (LSE)
Origin airport
Denver Intl.
Destination airport
La Crosse Municipal
Airlines serving
American Airlines
Roundtrip price
$444
Distance
742 mi

Denver to La Crosse Flights

The cheapest times to fly from Denver to La Crosse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to La Crosse are during the month of September. You can find some of the cheapest flights from Denver to La Crosse with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Denver to La Crosse

Sunday is one of the best days to book for cheap flights from Denver to La Crosse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Denver to La Crosse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to La Crosse in 2025. You can also book with separate airlines for your outbound and return journeys, from $314 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to La Crosse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to La Crosse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Denver Intl. Airport (DEN) to La Crosse Municipal Airport (LSE) cost?
Discover the latest flight deals from DEN to LSE by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from DEN to LSE?
The cheapest flights from DEN to LSE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from DEN to LSE?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from DEN to LSE. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Denver Intl. Airport (DEN) to La Crosse Municipal Airport (LSE)?
There aren’t any daily nonstop flights available from Denver Intl. Airport (DEN) to La Crosse Municipal Airport (LSE). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you’ll be soaring above the clouds in no time at all.
What day of the week has the most flights from DEN to LSE?
Generally you’ll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Denver Intl. Airport (DEN) to La Crosse Municipal Airport (LSE)?
To avoid possible delays on the Denver Intl. Airport (DEN) to La Crosse Municipal Airport (LSE) route, fly before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Denver Intl. Airport (DEN) to La Crosse Municipal Airport (LSE) last-minute?
Booking your ticket from DEN to LSE shortly before your getaway is typically more expensive. But if there’s some wiggle room with your travel times and dates, you could score a cheap last-minute fare.
Is it cheaper to book a DEN to LSE flight and hotel package?
You’ll generally save money by booking a DEN to LSE flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it’s easy to manage everything in one convenient place. After selecting your ideal accommodations and flights, consider adding extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Denver Intl. Airport (DEN) to La Crosse Municipal Airport (LSE)?
If you reserved your DEN to LSE flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you’d like more information.

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*Available to One Key members.