
Popular airlines from Denver Intl. Airport (DEN) to Greenville-Spartanburg Intl. Airport (GSP)
- Delta
Delta
- American Airlines
American Airlines
- United
United
- Southwest Airlines
Southwest Airlines
Cheap Flights from Denver to Greenville (DEN-GSP)
Prices were available within the past 7 days and start at $135 for one-way flights and $263 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Frequently asked questions
Travel information
Travel information
Origin airport | Denver Intl. |
Destination airport | Greenville-Spartanburg Intl. |
Airlines serving | American Airlines, Delta, Southwest Airlines, United |
Roundtrip price | $263 |
Distance | 1275 mi |
Book with confidence
Book with confidence
The cheapest times to fly from Denver to Greenville
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to Greenville are during the month of May. You can find some of the cheapest flights from Denver to Greenville with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Denver to Greenville
Sunday is one of the best days to book for cheap flights from Denver to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Denver to Greenville
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $135 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Be inspired and discover more with Expedia
Be inspired and discover more with Expedia
Flights
- Frontier Airlines Denver (DEN) to Miami (MIA) flights
- Frontier Airlines Denver (DEN) to Chicago (ORD) flights
- Aeromexico Denver (DEN) to Mexico City (MEX) flights
- United Denver (DEN) to Newark Liberty Intl. Airport (EWR) flights
- Alaska Airlines Denver (DEN) to Honolulu (HNL) flights
- Frontier Airlines Denver (DEN) to Tampa (TPA) flights
- Frontier Airlines Denver (DEN) to Los Angeles (LAX) flights
- Frontier Airlines Denver (DEN) to Phoenix (PHX) flights
- Delta Los Angeles (LAX) to Greenville (GSP) flights
- United Newark Liberty Intl. Airport (EWR) to Greenville (GSP) flights
- Delta New York (LGA) to Greenville (GSP) flights
- Delta Tampa (TPA) to Greenville (GSP) flights
- United Chicago (ORD) to Greenville (GSP) flights
- American Airlines Washington (DCA) to Greenville (GSP) flights
- American Airlines Miami (MIA) to Greenville (GSP) flights
- United Portland (PDX) to Greenville (GSP) flights
- Delta Minneapolis (MSP) to Greenville (GSP) flights
- Frontier Airlines Denver (DEN) to New York (LGA) flights
- JetBlue Airways Denver (DEN) to Fort Lauderdale (FLL) flights
- Brussels Airlines
- Alaska Airlines
- Air Canada
- Delta
- Iberia
- Aeromexico
- JetBlue Airways
- American Airlines
- Turkish Airlines
- Volaris
- Sun Country Airlines
- Swiss International Air Lines
- British Airways
- United
- Frontier Airlines
- Lufthansa
- Flights from Denver (DEN) to Miami (MIA)
- Flights from Denver (DEN) to Chicago (ORD)
- Flights from Denver (DEN) to Mexico City (MEX)
- Flights from Denver (DEN) to Las Vegas (LAS)
- Flights from Denver (DEN) to Orlando (MCO)
- Flights from Denver (DEN) to Newark Liberty Intl. Airport (EWR)
- Flights from Denver (DEN) to Honolulu (HNL)
- Flights from Denver (DEN) to Tampa (TPA)
- Flights from Denver (DEN) to Cancun (CUN)
- Flights from Denver (DEN) to Los Angeles (LAX)
- Flights from Denver (DEN) to Phoenix (PHX)
- Flights from San Diego (SAN) to Denver (DEN)
- Flights from Los Angeles (LAX) to Denver (DEN)
- Flights from Kansas City (MCI) to Denver (DEN)
- Flights from Houston (IAH) to Denver (DEN)
- Flights from Chicago (ORD) to Denver (DEN)
- Flights from St. Louis (STL) to Denver (DEN)
- Flights from Salt Lake City (SLC) to Denver (DEN)
- Flights from Seattle (SEA) to Denver (DEN)
- Flights from Detroit (DTW) to Denver (DEN)
- Flights from Phoenix (PHX) to Denver (DEN)
- Flights from Dallas (DFW) to Denver (DEN)
- Flights from Philadelphia (PHL) to Denver (DEN)
- Flights from Portland (PDX) to Denver (DEN)
- Flights from Minneapolis (MSP) to Denver (DEN)
- Flights from Orlando (MCO) to Denver (DEN)
- Flights from Atlanta (ATL) to Denver (DEN)
- Flights from Charlotte (CLT) to Denver (DEN)
- Flights from Boston (BOS) to Denver (DEN)
- Flights from Denver (DEN) to San Diego (SAN)
- Flights from Flint (FNT) to Greenville (GSP)
- Flights from Miami (MIA) to Greenville (GSP)
- Flights from Los Angeles (LAX) to Greenville (GSP)
- Flights from New York (LGA) to Greenville (GSP)
- Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
- Flights from Portland (PDX) to Greenville (GSP)
- Flights from Boston (BOS) to Greenville (GSP)
- Flights from Chicago (ORD) to Greenville (GSP)
- Flights from Detroit (DTW) to Greenville (GSP)
- Flights from Minneapolis (MSP) to Greenville (GSP)
- Flights from Tampa (TPA) to Greenville (GSP)
- Flights from Washington (DCA) to Greenville (GSP)
- Flights from Denver (DEN) to Puerto Vallarta (PVR)
- Flights from Denver (DEN) to New York (LGA)
- Flights from Denver (DEN) to Seattle (SEA)
- Flights from Denver (DEN) to Houston (IAH)
- Flights from Denver (DEN) to Atlanta (ATL)
- Flights from Denver (DEN) to Dallas (DFW)
- Flights from Denver (DEN) to Fort Lauderdale (FLL)
- Flights from Denver (DEN) to San José del Cabo (SJD)
- Flights to Washington
- Flights to Chicago
- Flights to San Antonio
- Flights to Orlando
- Flights to San Diego
- Flights to Houston
- Flights to Los Angeles
- Flights to Honolulu
- Flights to New Orleans
- Flights to Boston
- Flights to Fort Lauderdale
- Flights to Miami
- Flights to Pigeon Forge
- Flights to Nashville
- Flights to San Francisco
- Flights to Las Vegas
- Flights to Atlanta
- Flights to Gatlinburg
- Flights to Key West
- Flights to New York
- Flights from Cheyenne Regional
- Flights from Fort Collins-Loveland Municipal
- Flights from Colorado Springs
- Flights from Yampa Valley
- Flights from Pitkin County
- Flights from Laramie Regional
- Flights from Pueblo Memorial
- Flights from Rocky Mountain Metropolitan
- Flights from Western Nebraska Regional
- Flights from Eagle County Regional