$74 Cheap Flights from Denver (DEN) to Des Moines (DSM)

View $74 flight on Wed, May 21, 2025Opens in a new window

Popular airlines from Denver Intl. Airport (DEN) to Des Moines International Airport (DSM)

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Find available prices by choosing your travel dates.

Cheap Flights from Denver to Des Moines (DEN-DSM)

Prices were available within the past 7 days and start at $74 for one-way flights and $143 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Wed, May 7 - Wed, May 14
DEN
Denver
DSM
Des Moines
$143 Roundtrip, found 1 day ago
$143
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, May 7 from Denver to Des Moines, returning Wed, May 14, priced at $143 found 1 day ago
Frontier Airlines
Wed, May 7 - Mon, May 12
DEN
Denver
DSM
Des Moines
$148 Roundtrip, found 7 hours ago
$148
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Wed, May 7 from Denver to Des Moines, returning Mon, May 12, priced at $148 found 7 hours ago
Frontier Airlines
Wed, May 21 - Sun, May 25
DEN
Denver
DSM
Des Moines
$155 Roundtrip, found 6 days ago
$155
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, May 21 from Denver to Des Moines, returning Sun, May 25, priced at $155 found 6 days ago
Southwest Airlines
Wed, May 21 - Sun, May 25
DEN
Denver
DSM
Des Moines
$159 Roundtrip, found 6 days ago
$159
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, May 21 from Denver to Des Moines, returning Sun, May 25, priced at $159 found 6 days ago
Southwest Airlines
Sat, May 24 - Sun, May 25
DEN
Denver
DSM
Des Moines
$161 Roundtrip, found 17 hours ago
$161
Roundtrip
found 17 hours ago
Select Southwest Airlines flight, departing Sat, May 24 from Denver to Des Moines, returning Sun, May 25, priced at $161 found 17 hours ago
United
Sat, May 24 - Sun, May 25
DEN
Denver
DSM
Des Moines
$161 Roundtrip, found 17 hours ago
$161
Roundtrip
found 17 hours ago
Select United flight, departing Sat, May 24 from Denver to Des Moines, returning Sun, May 25, priced at $161 found 17 hours ago
Frontier Airlines
Fri, Jun 27 - Wed, Jul 2
DEN
Denver
DSM
Des Moines
$163 Roundtrip, found 15 hours ago
$163
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Fri, Jun 27 from Denver to Des Moines, returning Wed, Jul 2, priced at $163 found 15 hours ago
Frontier Airlines
Fri, Jun 27 - Mon, Jun 30
DEN
Denver
DSM
Des Moines
$164 Roundtrip, found 6 hours ago
$164
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Fri, Jun 27 from Denver to Des Moines, returning Mon, Jun 30, priced at $164 found 6 hours ago
American Airlines
Sat, May 24 - Sun, May 25
DEN
Denver
DSM
Des Moines
$174 Roundtrip, found 17 hours ago
$174
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Sat, May 24 from Denver to Des Moines, returning Sun, May 25, priced at $174 found 17 hours ago
Delta
Wed, May 21 - Sun, May 25
DEN
Denver
DSM
Des Moines
$179 Roundtrip, found 6 days ago
$179
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, May 21 from Denver to Des Moines, returning Sun, May 25, priced at $179 found 6 days ago

Frequently asked questions

How much does a flight from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) cost?
Cheap return flights from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) start at $155. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Frontier Airlines and Southwest Airlines flight leaving DEN on May 21 2025 and touching down at DSM. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from DEN to DSM?
The cheapest flights from DEN to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
You can fly nonstop from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) on a United Airlines flight.
What is the cheapest airline that flies from DEN to DSM?
Currently, the cheapest carrier operating one-way flights from DEN to DSM is Frontier Airlines. You can take off on this route from $74. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from DEN on May 21 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
With an average of 5 direct flights that operate from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) each day, you’ll be jetting off in no time.
What are the most popular departure times for flights from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
More travelers fly between DEN and DSM at 5 PM than at any other point in the day. Looking to skip the crowds? Pick a flight outside the busiest times and you could save on your fare as well.
What day of the week has the most flights from DEN to DSM?
If you jet off on a Monday, you’ll get the largest range of choices for flights from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM).
What is the earliest flight from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
The first flight of the day jetting off from Denver Intl. Airport (DEN) is at around 9:55AM UTC-7. Hop on this flight and you’ll touch down at Des Moines Intl. Airport (DSM) at approximately 12:55PM UTC-6. The total time in the air is 2h.
How long does it take to fly from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
Flights from DEN to DSM have an average travel time of 1 hour and 50 minutes. The distance between the two is 590 mi.
What is the best time to fly from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
Opt for a flight from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) that takes off before 3 PM to reduce the risk of cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Des Moines from Denver Intl. Airport (DEN)?
If you’re on a direct flight from Denver Intl. Airport (DEN) to Des Moines, Des Moines Intl. Airport (DSM) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from DEN to DSM are generally more expensive. For the cheapest rates, start searching for flights well ahead of time. That said, if you can play around with your travel dates, you may find a cheap fare right before your journey.
Is it cheaper to book a DEN to DSM flight and hotel package?
Opting for a DEN to DSM flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Select from our impressive range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Denver Intl. Airport (DEN) to Des Moines Intl. Airport (DSM)?
If you reserved your DEN to DSM flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.
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