$163 Cheap Flights from Columbus (CMH) to Santo Domingo (SDQ)

View $163 flight on Wed, Jun 18, 2025Opens in a new window

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to Las Americas Intl. Airport (SDQ)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.

Cheap Flights from Columbus to Santo Domingo (CMH-SDQ)

Prices were available within the past 7 days and start at $163 for one-way flights and $356 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Mon, Jun 2 - Wed, Jun 11
CMH
Columbus
SDQ
Santo Domingo
$356 Roundtrip, found 1 day ago
$356
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Mon, Jun 2 from Columbus to Santo Domingo, returning Wed, Jun 11, priced at $356 found 1 day ago
Spirit Airlines
Mon, May 19 - Mon, Jun 2
CMH
Columbus
SDQ
Santo Domingo
$359 Roundtrip, found 6 days ago
$359
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Mon, May 19 from Columbus to Santo Domingo, returning Mon, Jun 2, priced at $359 found 6 days ago
Spirit Airlines
Sat, May 3 - Sat, May 10
CMH
Columbus
SDQ
Santo Domingo
$360 Roundtrip, found 1 day ago
$360
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Sat, May 3 from Columbus to Santo Domingo, returning Sat, May 10, priced at $360 found 1 day ago
Spirit Airlines
Tue, Aug 19 - Mon, Aug 25
CMH
Columbus
SDQ
Santo Domingo
$366 Roundtrip, found 3 days ago
$366
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, Aug 19 from Columbus to Santo Domingo, returning Mon, Aug 25, priced at $366 found 3 days ago
Spirit Airlines
Mon, Jun 16 - Tue, Jun 24
CMH
Columbus
SDQ
Santo Domingo
$368 Roundtrip, found 3 hours ago
$368
Roundtrip
found 3 hours ago
Select Spirit Airlines flight, departing Mon, Jun 16 from Columbus to Santo Domingo, returning Tue, Jun 24, priced at $368 found 3 hours ago
Spirit Airlines
Mon, Jun 16 - Wed, Jun 25
CMH
Columbus
SDQ
Santo Domingo
$371 Roundtrip, found 12 hours ago
$371
Roundtrip
found 12 hours ago
Select Spirit Airlines flight, departing Mon, Jun 16 from Columbus to Santo Domingo, returning Wed, Jun 25, priced at $371 found 12 hours ago
Frontier Airlines
Sat, Aug 16 - Sun, Aug 17
CMH
Columbus
SDQ
Santo Domingo
$389 Roundtrip, found 15 hours ago
$389
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Sat, Aug 16 from Columbus to Santo Domingo, returning Sun, Aug 17, priced at $389 found 15 hours ago
American Airlines
Tue, Dec 9 - Tue, Jan 13
CMH
Columbus
SDQ
Santo Domingo
$465 Roundtrip, found 19 hours ago
$465
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Dec 9 from Columbus to Santo Domingo, returning Tue, Jan 13, priced at $465 found 19 hours ago
Delta
Tue, Jun 3 - Tue, Jul 1
CMH
Columbus
SDQ
Santo Domingo
$465 Roundtrip, found 4 hours ago
$465
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Jun 3 from Columbus to Santo Domingo, returning Tue, Jul 1, priced at $465 found 4 hours ago
United
Wed, May 28 - Wed, Jun 11
CMH
Columbus
SDQ
Santo Domingo
$465 Roundtrip, found 14 hours ago
$465
Roundtrip
found 14 hours ago
Select United flight, departing Wed, May 28 from Columbus to Santo Domingo, returning Wed, Jun 11, priced at $465 found 14 hours ago
Flights from Columbus (CMH) to Santo Domingo (SDQ)
Origin airport
John Glenn Columbus Intl.
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Copa, Delta, Frontier Airlines, Spirit Airlines, United
Roundtrip price
$356
Distance
1685 mi

Columbus to Santo Domingo Flights

The cheapest times to fly from Columbus to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbus to Santo Domingo are during the month of June. You can find some of the cheapest flights from Columbus to Santo Domingo with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Columbus to Santo Domingo

Sunday is one of the best days to book for cheap flights from Columbus to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Columbus to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbus to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $163 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbus to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbus to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from John Glenn Columbus Intl. Airport (CMH) to Las Americas Intl. Airport (SDQ) cost?
Discover the latest flight deals from CMH to SDQ by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from CMH to SDQ?
The cheapest flights from CMH to SDQ are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from CMH to SDQ?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from CMH to SDQ. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from John Glenn Columbus Intl. Airport (CMH) to Las Americas Intl. Airport (SDQ)?
There aren’t any daily direct flights available from John Glenn Columbus Intl. Airport (CMH) to Las Americas Intl. Airport (SDQ). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you’ll be cruising above the clouds in no time at all.
What day of the week has the most flights from CMH to SDQ?
You’ll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from John Glenn Columbus Intl. Airport (CMH) to Las Americas Intl. Airport (SDQ)?
Book a flight from John Glenn Columbus Intl. Airport (CMH) to Las Americas Intl. Airport (SDQ) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from John Glenn Columbus Intl. Airport (CMH) to Las Americas Intl. Airport (SDQ) last-minute?
Holding off until just before your departure to book a ticket from CMH to SDQ generally means paying more. While you might find some last-minute offers, they aren’t always guaranteed. Allow some flexibility in your schedule for the best chance of getting a bargain.
Is it cheaper to book a CMH to SDQ flight and hotel package?
Booking a CMH to SDQ flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from John Glenn Columbus Intl. Airport (CMH) to Las Americas Intl. Airport (SDQ)?
In most cases, you’re able to reschedule or cancel your CMH to SDQ flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline’s policies and fees on flight changes, or if you’d like further details, go to our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.