$115 Cheap Flights from Columbus (CMH) to Greenville (GSP)

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to Greenville-Spartanburg Intl. Airport (GSP)

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Find available prices by choosing your travel dates.

Cheap Flights from Columbus to Greenville (CMH-GSP)

Prices were available within the past 7 days and start at $115 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
United
American Airlines
Southwest Airlines
American Airlines
American Airlines
Delta
United
American Airlines
Southwest Airlines
Flights from Columbus (CMH) to Greenville (GSP)
Origin airport
John Glenn Columbus Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$228
Distance
354 mi

Columbus to Greenville Flights

The cheapest times to fly from Columbus to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbus to Greenville are during the month of May. You can find some of the cheapest flights from Columbus to Greenville with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Columbus to Greenville

Sunday is one of the best days to book for cheap flights from Columbus to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Columbus to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbus to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $115 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbus to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbus to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

Is it cheaper to buy a plane ticket from CMH to GSP last minute?
Being a spontaneous soul is an amazing way to see the world, but it isn’t necessarily the wisest way to get your hands on a bargain airfare. Consider booking your John Glenn Intl. Airport to Roger Milliken Field journey well in advance instead of waiting until the last minute. Based on flight pricing and demand studies in 2022, we have found that the best time to book domestic flights is between 28 – 35 days ahead of the departure date, and international flights three to four months in advance. Leave your spontaneous side for when you’re discovering Roger Milliken Field!
What airports do you fly into for Greenville from Columbus?
Greenville-Spartanburg Intl. Airport (GSP), Asheville Regional Airport (AVL) and Greenville, SC (GMU-Greenville Downtown) are your choices when flying from Columbus to Greenville. Around 11 mi east of the center of Greenville, Greenville-Spartanburg Intl. Airport (GSP) is the city’s major gateway. Consider things such as flight arrival and departure times and the distance to your hotel before deciding on an airport. Haywood Mall and Furman University are a couple of leading attractions to add to your must-see list when you arrive at your destination.
Can I change the date of my flight from John Glenn Columbus Intl. Airport (CMH) to Roger Milliken Field?
It’s so easy to make amendments to your CMH to GSP journey yourself. Access your itinerary via the Expedia Trips portal and click on “change flight.” Look around for new flights and secure the one that works best with your plans. You’ll see an estimate of any flight change costs. Alternatively, head to our Customer Service portal to connect with our Virtual Agent and get answers to all your questions.

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