$211 Cheap Flights from Charlotte (CLT) to Panama City (PTY)

View $211 flight on Wed, Aug 20, 2025Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)

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Find available prices by choosing your travel dates.

Cheap Flights from Charlotte to Panama City (CLT-PTY)

Prices were available within the past 7 days and start at $211 for one-way flights and $447 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Aug 13 - Tue, Aug 19
CLT
Charlotte
PTY
Panama City
$447 Roundtrip, found 2 hours ago
$447
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Aug 13 from Charlotte to Panama City, returning Tue, Aug 19, priced at $447 found 2 hours ago
Delta
Wed, Aug 13 - Tue, Aug 19
CLT
Charlotte
PTY
Panama City
$447 Roundtrip, found 2 hours ago
$447
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Aug 13 from Charlotte to Panama City, returning Tue, Aug 19, priced at $447 found 2 hours ago
United
Wed, Aug 13 - Tue, Aug 19
CLT
Charlotte
PTY
Panama City
$447 Roundtrip, found 2 hours ago
$447
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Aug 13 from Charlotte to Panama City, returning Tue, Aug 19, priced at $447 found 2 hours ago
American Airlines
Sun, Sep 7 - Tue, Sep 23
CLT
Charlotte
PTY
Panama City
$452 Roundtrip, found 13 hours ago
$452
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sun, Sep 7 from Charlotte to Panama City, returning Tue, Sep 23, priced at $452 found 13 hours ago
Delta
Sun, Jul 13 - Thu, Jul 24
CLT
Charlotte
PTY
Panama City
$454 Roundtrip, found 6 hours ago
$454
Roundtrip
found 6 hours ago
Select Delta flight, departing Sun, Jul 13 from Charlotte to Panama City, returning Thu, Jul 24, priced at $454 found 6 hours ago
United
Mon, Jun 16 - Mon, Jun 23
CLT
Charlotte
PTY
Panama City
$455 Roundtrip, found 2 days ago
$455
Roundtrip
found 2 days ago
Select United flight, departing Mon, Jun 16 from Charlotte to Panama City, returning Mon, Jun 23, priced at $455 found 2 days ago
United
Thu, Aug 14 - Tue, Aug 19
CLT
Charlotte
PTY
Panama City
$457 Roundtrip, found 6 hours ago
$457
Roundtrip
found 6 hours ago
Select United flight, departing Thu, Aug 14 from Charlotte to Panama City, returning Tue, Aug 19, priced at $457 found 6 hours ago
American Airlines
Tue, Sep 16 - Tue, Sep 30
CLT
Charlotte
PTY
Panama City
$459 Roundtrip, found 14 hours ago
$459
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Tue, Sep 16 from Charlotte to Panama City, returning Tue, Sep 30, priced at $459 found 14 hours ago
Delta
Sun, Jun 22 - Tue, Jul 1
CLT
Charlotte
PTY
Panama City
$460 Roundtrip, found 1 day ago
$460
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Jun 22 from Charlotte to Panama City, returning Tue, Jul 1, priced at $460 found 1 day ago
Copa
Wed, Aug 20 - Sun, Aug 24
CLT
Charlotte
PTY
Panama City
$1,133 Roundtrip, found 1 hour ago
$1,133
Roundtrip
found 1 hour ago
Select Copa flight, departing Wed, Aug 20 from Charlotte to Panama City, returning Sun, Aug 24, priced at $1,133 found 1 hour ago

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) cost?
Discover the latest flight deals from CLT to PTY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from CLT to PTY?
The cheapest flights from CLT to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from CLT to PTY?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from CLT to PTY. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
There are no daily direct flights available from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you’ll be on your way in no time at all.
What day of the week has the most flights from CLT to PTY?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
Book a flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) that takes off before 3 PM to reduce the risk of cancellations. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY) last-minute?
Booking your ticket from CLT to PTY right before your journey is usually more expensive. But if there’s some wiggle room with your travel times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a CLT to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a CLT to PTY flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place takes the hassle out of travel planning. Simply secure your flights and choose from our wide range of hotels, then customize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to Tocumen Intl. Airport (PTY)?
If you booked your CLT to PTY flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.
*Available to One Key members.