$167 Cheap Flights from Charlotte (CLT) to Key West (EYW)

View $167 flight on Mon, Jun 16, 2025Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)

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Find available prices by choosing your travel dates.

Cheap Flights from Charlotte to Key West (CLT-EYW)

Prices were available within the past 7 days and start at $167 for one-way flights and $343 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Sep 18 - Thu, Sep 25
CLT
Charlotte
EYW
Key West
$343 Roundtrip, found 1 day ago
$343
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Sep 18 from Charlotte to Key West, returning Thu, Sep 25, priced at $343 found 1 day ago
Delta
Wed, May 14 - Sat, May 24
CLT
Charlotte
EYW
Key West
$351 Roundtrip, found 1 day ago
$351
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 14 from Charlotte to Key West, returning Sat, May 24, priced at $351 found 1 day ago
Delta
Wed, May 14 - Fri, May 23
CLT
Charlotte
EYW
Key West
$362 Roundtrip, found 1 day ago
$362
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 14 from Charlotte to Key West, returning Fri, May 23, priced at $362 found 1 day ago
American Airlines
Mon, May 19 - Fri, May 23
CLT
Charlotte
EYW
Key West
$362 Roundtrip, found 1 day ago
$362
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, May 19 from Charlotte to Key West, returning Fri, May 23, priced at $362 found 1 day ago
Delta
Fri, May 16 - Sat, May 24
CLT
Charlotte
EYW
Key West
$370 Roundtrip, found 1 day ago
$370
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, May 16 from Charlotte to Key West, returning Sat, May 24, priced at $370 found 1 day ago
Delta
Sun, May 25 - Fri, May 30
CLT
Charlotte
EYW
Key West
$376 Roundtrip, found 12 hours ago
$376
Roundtrip
found 12 hours ago
Select Delta flight, departing Sun, May 25 from Charlotte to Key West, returning Fri, May 30, priced at $376 found 12 hours ago
Delta
Fri, May 16 - Fri, May 23
CLT
Charlotte
EYW
Key West
$381 Roundtrip, found 1 day ago
$381
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, May 16 from Charlotte to Key West, returning Fri, May 23, priced at $381 found 1 day ago
American Airlines
Sun, May 25 - Fri, May 30
CLT
Charlotte
EYW
Key West
$393 Roundtrip, found 12 hours ago
$393
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sun, May 25 from Charlotte to Key West, returning Fri, May 30, priced at $393 found 12 hours ago
United
Sun, May 25 - Fri, May 30
CLT
Charlotte
EYW
Key West
$396 Roundtrip, found 12 hours ago
$396
Roundtrip
found 12 hours ago
Select United flight, departing Sun, May 25 from Charlotte to Key West, returning Fri, May 30, priced at $396 found 12 hours ago
American Airlines
Mon, May 19 - Fri, May 23
CLT
Charlotte
EYW
Key West
$397 Roundtrip, found 1 day ago
$397
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, May 19 from Charlotte to Key West, returning Fri, May 23, priced at $397 found 1 day ago
Flights from Charlotte (CLT) to Key West (EYW)
Origin airport
Charlotte-Douglas Intl.
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$342
Distance
738 mi

Charlotte to Key West Flights

The cheapest times to fly from Charlotte to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to Key West are during the month of September. You can find some of the cheapest flights from Charlotte to Key West with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Charlotte to Key West

Sunday is one of the best days to book for cheap flights from Charlotte to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Charlotte to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $167 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW) cost?
You can score affordable return tickets from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW) starting from $447. Snag a seat and start your adventure. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a American Airlines flight leaving CLT on May 18 2025 and touching down at EYW. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from CLT to EYW?
The cheapest flights from CLT to EYW are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)?
Jump on a nonstop flight with American Airlines and head straight from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW).
What is the cheapest airline that flies from CLT to EYW?
Take off from CLT to EYW with American Airlines. This carrier currently has the cheapest one-way ticket for this route, starting from $335. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from CLT on July 14 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)?
Every day on average, 3 direct flights take off from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW). Pick the departure time that works for you.
What are the most popular departure times for flights from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)?
The 9 AM departures from CLT to EYW are the busiest. Prices can be higher for these popular slots. If you want to save on your fare, pick a less crowded time to fly.
What day of the week has the most flights from CLT to EYW?
Depart on a Sunday if you’re looking for the biggest selection of flights from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW).
What is the earliest flight from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)?
Charlotte-Douglas Intl. Airport (CLT)’s earliest flight to Key West Intl. Airport (EYW) leaves at approximately 9:40AM UTC-5. With a total flight time of 2h 28m, you’ll arrive at around 12:08PM UTC-5.
How long does it take to fly from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)?
Flights from CLT to EYW have an average travel time of 2 hours and 22 minutes. The total distance between these two airports is 740 mi.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)?
To touch down at Key West Intl. Airport (EYW) on time, choose a flight that leaves Charlotte-Douglas Intl. Airport (CLT) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Key West from Charlotte-Douglas Intl. Airport (CLT)?
If you’ve booked a direct flight from Charlotte-Douglas Intl. Airport (CLT) to Key West, Key West Intl. Airport (EYW) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW) last-minute?
Holding off until just before your departure to book your flight from CLT to EYW often results in higher prices. While it’s possible to find some last-minute deals, they’re not always guaranteed. Allow some flexibility in your schedule for a better chance of getting a bargain.
Is it cheaper to book a CLT to EYW flight and hotel package?
Compared with arranging flights and hotels separately, booking a CLT to EYW flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place will take the stress out of travel planning. Just secure your flights and choose from our wide range of hotels, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to Key West Intl. Airport (EYW)?
Usually, it’s possible to reschedule or cancel your CLT to EYW flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline’s policies in your itinerary to see what changes are allowed and whether any costs are involved. You’ll also find more information on our Customer Service portal.

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*Available to One Key members.