$457 Cheap Flights from Charlotte (CLT) to Brussels (BRU)

View $457 flight on Wed, Sep 10, 2025Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Brussels Airport (BRU)

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Find available prices by choosing your travel dates.

Cheap Flights from Charlotte to Brussels (CLT-BRU)

Prices were available within the past 7 days and start at $457 for one-way flights and $630 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Nov 5 - Wed, Nov 19
CLT
Charlotte
BRU
Brussels
$630 Roundtrip, found 3 hours ago
$630
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Nov 5 from Charlotte to Brussels, returning Wed, Nov 19, priced at $630 found 3 hours ago
Air Canada
Sun, Aug 17 - Tue, Aug 26
CLT
Charlotte
BRU
Brussels
$632 Roundtrip, found 4 days ago
$632
Roundtrip
found 4 days ago
Select Air Canada flight, departing Sun, Aug 17 from Charlotte to Brussels, returning Tue, Aug 26, priced at $632 found 4 days ago
Virgin Atlantic
Sun, Aug 17 - Tue, Aug 26
CLT
Charlotte
BRU
Brussels
$634 Roundtrip, found 4 days ago
$634
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Sun, Aug 17 from Charlotte to Brussels, returning Tue, Aug 26, priced at $634 found 4 days ago
United
Tue, Oct 14 - Tue, Dec 16
CLT
Charlotte
BRU
Brussels
$634 Roundtrip, found 4 days ago
$634
Roundtrip
found 4 days ago
Select United flight, departing Tue, Oct 14 from Charlotte to Brussels, returning Tue, Dec 16, priced at $634 found 4 days ago
Virgin Atlantic
Sun, Aug 3 - Tue, Aug 19
CLT
Charlotte
BRU
Brussels
$634 Roundtrip, found 2 days ago
$634
Roundtrip
found 2 days ago
Select Virgin Atlantic flight, departing Sun, Aug 3 from Charlotte to Brussels, returning Tue, Aug 19, priced at $634 found 2 days ago
Air Canada
Wed, Nov 5 - Wed, Nov 19
CLT
Charlotte
BRU
Brussels
$636 Roundtrip, found 3 hours ago
$636
Roundtrip
found 3 hours ago
Select Air Canada flight, departing Wed, Nov 5 from Charlotte to Brussels, returning Wed, Nov 19, priced at $636 found 3 hours ago
Delta
Mon, Oct 6 - Thu, Nov 20
CLT
Charlotte
BRU
Brussels
$640 Roundtrip, found 1 day ago
$640
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Oct 6 from Charlotte to Brussels, returning Thu, Nov 20, priced at $640 found 1 day ago
American Airlines
Wed, Nov 5 - Wed, Nov 19
CLT
Charlotte
BRU
Brussels
$649 Roundtrip, found 3 hours ago
$649
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Wed, Nov 5 from Charlotte to Brussels, returning Wed, Nov 19, priced at $649 found 3 hours ago
Iberia
Mon, Dec 1 - Wed, Dec 10
CLT
Charlotte
BRU
Brussels
$650 Roundtrip, found 8 hours ago
$650
Roundtrip
found 8 hours ago
Select Iberia flight, departing Mon, Dec 1 from Charlotte to Brussels, returning Wed, Dec 10, priced at $650 found 8 hours ago
British Airways
Tue, Oct 14 - Tue, Dec 16
CLT
Charlotte
BRU
Brussels
$650 Roundtrip, found 4 days ago
$650
Roundtrip
found 4 days ago
Select British Airways flight, departing Tue, Oct 14 from Charlotte to Brussels, returning Tue, Dec 16, priced at $650 found 4 days ago
Flights from Charlotte (CLT) to Brussels (BRU)
Origin airport
Charlotte-Douglas Intl.
Destination airport
Brussels - National
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, British Airways, Brussels Airlines, Delta, Finnair, Iberia, KLM, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, United, Virgin Atlantic
Roundtrip price
$630
Distance
4197 mi

Charlotte to Brussels Flights

The cheapest times to fly from Charlotte to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to Brussels are during the month of November. You can find some of the cheapest flights from Charlotte to Brussels with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Charlotte to Brussels

Sunday is one of the best days to book for cheap flights from Charlotte to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Charlotte to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $457 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to Brussels - National Airport (BRU) cost?
Discover the latest flight deals from CLT to BRU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from CLT to BRU?
The cheapest flights from CLT to BRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from CLT to BRU?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from CLT to BRU. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to Brussels - National Airport (BRU)?
Direct flights from Charlotte-Douglas Intl. Airport (CLT) to Brussels - National Airport (BRU) aren’t available daily, so you’ll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and click on either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from CLT to BRU?
You’ll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to Brussels - National Airport (BRU)?
Book a flight from Charlotte-Douglas Intl. Airport (CLT) to Brussels - National Airport (BRU) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to Brussels - National Airport (BRU) last-minute?
Booking your ticket from CLT to BRU right before your trip is usually more expensive. However, if there’s some wiggle room with your travel times and dates, you could score a cheap last-minute fare.
Is it cheaper to book a CLT to BRU flight and hotel package?
Compared with arranging flights and hotels separately, booking a CLT to BRU flight and hotel package with Expedia could result in significant savings. Better still, having it all in one place takes the hassle out of planning your trip. Just secure your flights and select from our extensive range of stays, then customize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to Brussels - National Airport (BRU)?
In most cases, you can reschedule or cancel your CLT to BRU flight. However, additional fees may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline’s guidelines and fees on flight changes, or if you need more information, head to our Customer Service portal.

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*Available to One Key members.