$149 Cheap Flights from Charleston (CHS) to Santo Domingo (SDQ)

View $149 flight on Sat, May 10, 2025Opens in a new window

Popular airlines from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)

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Find available prices by choosing your travel dates.

Cheap Flights from Charleston to Santo Domingo (CHS-SDQ)

Prices were available within the past 7 days and start at $149 for one-way flights and $290 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Sat, May 10 - Fri, May 30
CHS
Charleston
SDQ
Santo Domingo
$290 Roundtrip, found 6 days ago
$290
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Sat, May 10 from Charleston to Santo Domingo, returning Fri, May 30, priced at $290 found 6 days ago
Spirit Airlines
Sat, May 10 - Fri, May 16
CHS
Charleston
SDQ
Santo Domingo
$329 Roundtrip, found 3 days ago
$329
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Sat, May 10 from Charleston to Santo Domingo, returning Fri, May 16, priced at $329 found 3 days ago
Spirit Airlines
Sat, May 24 - Wed, Jun 4
CHS
Charleston
SDQ
Santo Domingo
$347 Roundtrip, found 2 days ago
$347
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Sat, May 24 from Charleston to Santo Domingo, returning Wed, Jun 4, priced at $347 found 2 days ago
Spirit Airlines
Sat, May 24 - Fri, Jun 6
CHS
Charleston
SDQ
Santo Domingo
$369 Roundtrip, found 21 hours ago
$369
Roundtrip
found 21 hours ago
Select Spirit Airlines flight, departing Sat, May 24 from Charleston to Santo Domingo, returning Fri, Jun 6, priced at $369 found 21 hours ago
Spirit Airlines
Sat, Jun 14 - Sat, Aug 2
CHS
Charleston
SDQ
Santo Domingo
$379 Roundtrip, found 3 days ago
$379
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Sat, Jun 14 from Charleston to Santo Domingo, returning Sat, Aug 2, priced at $379 found 3 days ago
Spirit Airlines
Fri, May 2 - Fri, May 9
CHS
Charleston
SDQ
Santo Domingo
$381 Roundtrip, found 2 days ago
$381
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Fri, May 2 from Charleston to Santo Domingo, returning Fri, May 9, priced at $381 found 2 days ago
Frontier Airlines
Fri, May 9 - Fri, May 16
CHS
Charleston
SDQ
Santo Domingo
$390 Roundtrip, found 3 days ago
$390
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, May 9 from Charleston to Santo Domingo, returning Fri, May 16, priced at $390 found 3 days ago
JetBlue Airways
Sat, Jun 14 - Wed, Jun 18
CHS
Charleston
SDQ
Santo Domingo
$403 Roundtrip, found 3 hours ago
$403
Roundtrip
found 3 hours ago
Select JetBlue Airways flight, departing Sat, Jun 14 from Charleston to Santo Domingo, returning Wed, Jun 18, priced at $403 found 3 hours ago
United
Fri, May 2 - Fri, May 9
CHS
Charleston
SDQ
Santo Domingo
$414 Roundtrip, found 2 days ago
$414
Roundtrip
found 2 days ago
Select United flight, departing Fri, May 2 from Charleston to Santo Domingo, returning Fri, May 9, priced at $414 found 2 days ago
American Airlines
Fri, May 2 - Fri, May 9
CHS
Charleston
SDQ
Santo Domingo
$415 Roundtrip, found 2 days ago
$415
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, May 2 from Charleston to Santo Domingo, returning Fri, May 9, priced at $415 found 2 days ago
Flights from Charleston (CHS) to Santo Domingo (SDQ)
Origin airport
Charleston Intl.
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Copa, Delta, JetBlue Airways, Spirit Airlines, United
Roundtrip price
$290
Distance
1187 mi

Charleston to Santo Domingo Flights

The cheapest times to fly from Charleston to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to Santo Domingo are during the month of May. You can find some of the cheapest flights from Charleston to Santo Domingo with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Charleston to Santo Domingo

Sunday is one of the best days to book for cheap flights from Charleston to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Charleston to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $149 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) cost?
Discover the latest flight deals from CHS to SDQ by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from CHS to SDQ?
The cheapest flights from CHS to SDQ are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from CHS to SDQ?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from CHS to SDQ. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)?
Nonstop flights from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) aren’t available daily, so you’ll have to take a flight with a layover. Explore your options with Expedia’s filters. Enter your dates and select either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from CHS to SDQ?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)?
To avoid potential delays on the Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) route, aim to fly before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ) last-minute?
Booking your flight from CHS to SDQ right before your trip is generally more expensive. However, if there’s some wiggle room with your travel times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a CHS to SDQ flight and hotel package?
Compared with arranging hotels and flights separately, booking a CHS to SDQ flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place takes the hassle out of travel planning. Just secure your flights and select from our wide range of stays, then tailor your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Charleston Intl. Airport (CHS) to Las Americas Intl. Airport (SDQ)?
You can usually cancel or reschedule your CHS to SDQ flight. However, if it’s been more than 24 hours since booking, additional charges may apply. Check your airline’s policies in your itinerary to see what changes are possible and whether any costs are involved. You’ll also find more details on our Customer Service portal.

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*Available to One Key members.