$83 Cheap Flights from Buffalo (BUF) to St. Louis (STL)

View $83 flight on Wed, Jun 18, 2025Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to St. Louis Lambert Intl. Airport (STL)

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Find available prices by choosing your travel dates.

Cheap Flights from Buffalo to St. Louis (BUF-STL)

Prices were available within the past 7 days and start at $83 for one-way flights and $188 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sat, May 10 - Wed, May 14
BUF
Buffalo
STL
St. Louis
$188 Roundtrip, just found
$188
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, May 10 from Buffalo to St. Louis, returning Wed, May 14, priced at $188 just found
Southwest Airlines
Tue, Sep 2 - Wed, Sep 3
BUF
Buffalo
STL
St. Louis
$197 Roundtrip, found 4 hours ago
$197
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Tue, Sep 2 from Buffalo to St. Louis, returning Wed, Sep 3, priced at $197 found 4 hours ago
Frontier Airlines
Sun, Apr 27 - Wed, Apr 30
BUF
Buffalo
STL
St. Louis
$198 Roundtrip, just found
$198
Roundtrip
just found
Select Frontier Airlines flight, departing Sun, Apr 27 from Buffalo to St. Louis, returning Wed, Apr 30, priced at $198 just found
Southwest Airlines
Wed, Jun 18 - Sun, Jun 22
BUF
Buffalo
STL
St. Louis
$202 Roundtrip, found 1 day ago
$202
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Jun 18 from Buffalo to St. Louis, returning Sun, Jun 22, priced at $202 found 1 day ago
Southwest Airlines
Wed, Jun 18 - Sun, Jun 22
BUF
Buffalo
STL
St. Louis
$208 Roundtrip, found 1 day ago
$208
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Jun 18 from Buffalo to St. Louis, returning Sun, Jun 22, priced at $208 found 1 day ago
Frontier Airlines
Sun, Apr 27 - Fri, May 2
BUF
Buffalo
STL
St. Louis
$208 Roundtrip, just found
$208
Roundtrip
just found
Select Frontier Airlines flight, departing Sun, Apr 27 from Buffalo to St. Louis, returning Fri, May 2, priced at $208 just found
Southwest Airlines
Tue, Sep 2 - Wed, Sep 3
BUF
Buffalo
STL
St. Louis
$215 Roundtrip, found 4 hours ago
$215
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Tue, Sep 2 from Buffalo to St. Louis, returning Wed, Sep 3, priced at $215 found 4 hours ago
Delta
Fri, Jun 6 - Mon, Jun 9
BUF
Buffalo
STL
St. Louis
$232 Roundtrip, found 1 day ago
$232
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Jun 6 from Buffalo to St. Louis, returning Mon, Jun 9, priced at $232 found 1 day ago
American Airlines
Thu, May 29 - Mon, Jun 2
BUF
Buffalo
STL
St. Louis
$244 Roundtrip, found 1 hour ago
$244
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, May 29 from Buffalo to St. Louis, returning Mon, Jun 2, priced at $244 found 1 hour ago
United
Fri, Jun 6 - Mon, Jun 9
BUF
Buffalo
STL
St. Louis
$246 Roundtrip, found 1 day ago
$246
Roundtrip
found 1 day ago
Select United flight, departing Fri, Jun 6 from Buffalo to St. Louis, returning Mon, Jun 9, priced at $246 found 1 day ago
Flights from Buffalo (BUF) to St. Louis (STL)
Origin airport
Buffalo Niagara Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$188
Distance
672 mi

Buffalo to St. Louis Flights

The cheapest times to fly from Buffalo to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to St. Louis are during the month of May. You can find some of the cheapest flights from Buffalo to St. Louis with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Buffalo to St. Louis

Sunday is one of the best days to book for cheap flights from Buffalo to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Buffalo to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $83 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Lambert-St. Louis Intl. Airport (STL) cost?
Discover the latest flight deals from BUF to STL by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from BUF to STL?
The cheapest flights from BUF to STL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from BUF to STL?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from BUF to STL. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Lambert-St. Louis Intl. Airport (STL)?
Direct flights from Buffalo Niagara Intl. Airport (BUF) to Lambert-St. Louis Intl. Airport (STL) aren’t available daily, so you’ll have to take a flight with a layover. Explore your options with Expedia’s filters. Enter your travel dates and click on either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from BUF to STL?
Usually you’ll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Lambert-St. Louis Intl. Airport (STL)?
To reach Lambert-St. Louis Intl. Airport (STL) on schedule, opt for a flight that leaves Buffalo Niagara Intl. Airport (BUF) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Last-minute fares from BUF to STL are usually more expensive. To lock in the lowest prices, start searching for flights well ahead of time. That being said, if you can play around with your travel dates, you may score a cheap fare right before your trip.
Is it cheaper to book a BUF to STL flight and hotel package?
You’ll typically save money by booking a BUF to STL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it’s easy to manage everything in one place. After choosing your ideal flights and accommodations, you can add extras such as activities, tours and car rentals.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Lambert-St. Louis Intl. Airport (STL)?
Generally, it’s possible to reschedule or cancel your BUF to STL flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline’s policies in your itinerary to see what changes are allowed and if any costs are involved. You’ll also find more information on our Customer Service portal.

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*Available to One Key members.