Cheap Flights from Mesa (AZA) to Knoxville (TYS)

Popular airlines from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS)

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Find available prices by choosing your travel dates.
Flights from Mesa (AZA) to Knoxville (TYS)
Origin airport
Phoenix - Mesa Gateway
Destination airport
McGhee Tyson
Distance
1579 mi

Mesa to Knoxville Flights

The cheapest times to fly from Mesa to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mesa to Knoxville are during the month of . You can find some of the cheapest flights from Mesa to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mesa to Knoxville

Sunday is one of the best days to book for cheap flights from Mesa to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mesa to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mesa to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mesa to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mesa to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS) cost?
Discover the latest flight deals from AZA to TYS by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from AZA to TYS?
The cheapest flights from AZA to TYS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS)?
There’s no direct route from Mesa, AZ (AZA-Phoenix - Mesa Gateway) to McGhee Tyson Airport (TYS). However, you’ll find other airports that offer nonstop flights. Hop on your plane at Sky Harbor Intl. Airport (PHX) and fly straight to Knoxville without a layover.
What is the cheapest airline that flies from AZA to TYS?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from AZA to TYS. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS)?
Nonstop flights from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS) aren’t available daily, so you’ll need to take a flight with a layover. Explore your options with Expedia’s filters. Enter your travel details and choose either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from AZA to TYS?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can vary based on a range of factors, such as the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS)?
Book a flight from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS) last-minute?
Holding off until just before your departure to book a ticket from AZA to TYS generally means paying more. While it’s possible to find some last-minute deals, there’s no guarantee. Be flexible with your travel plans to boost your chances of snagging a bargain.
Is it cheaper to book an AZA to TYS flight and hotel package?
Securing an AZA to TYS flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our impressive range of hotels and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Phoenix - Mesa Gateway Airport (AZA) to McGhee Tyson Airport (TYS)?
It’s usually possible to cancel or reschedule your AZA to TYS flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline’s policies in your itinerary to see what changes are allowed and if any costs are involved. You’ll also find more details on our Customer Service portal.

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*Available to One Key members.