Cheap Flights from Mesa (AZA) to Sioux Falls (FSD)

Popular airlines from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD)

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Flights from Mesa (AZA) to Sioux Falls (FSD)
Origin airport
Phoenix - Mesa Gateway
Destination airport
Sioux Falls Regional
Distance
1072 mi

Mesa to Sioux Falls Flights

The cheapest times to fly from Mesa to Sioux Falls

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mesa to Sioux Falls are during the month of . You can find some of the cheapest flights from Mesa to Sioux Falls with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Mesa to Sioux Falls

Sunday is one of the best days to book for cheap flights from Mesa to Sioux Falls: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Mesa to Sioux Falls

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mesa to Sioux Falls in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mesa to Sioux Falls flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mesa to Sioux Falls airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD) cost?
Discover the latest flight deals from AZA to FSD by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from AZA to FSD?
The cheapest flights from AZA to FSD are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD)?
You can’t take a direct flight from Mesa, AZ (AZA-Phoenix - Mesa Gateway) to Sioux Falls Regional Airport (FSD). However, you can easily travel to Sioux Falls without any layovers by departing from Sky Harbor Intl. Airport (PHX).
What is the cheapest airline that flies from AZA to FSD?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from AZA to FSD. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD)?
On average, there is just 1 direct flight taking off from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD) every day. If this doesn’t fit your travel plans, consider flights with a layover. Just filter your search results on Expedia to include one or two stops to find the next best option.
What are the most popular departure times for flights from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD)?
Flights between AZA and FSD are their busiest at 10 AM. If you want a more relaxed experience and possibly cheaper fares, choose a time when demand is lower.
What day of the week has the most flights from AZA to FSD?
Friday has the most flights from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD). Consider leaving on this day and you’ll have a greater chance of finding a departure that fits your plans.
What is the earliest flight from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD)?
The earliest flight leaving from Phoenix - Mesa Gateway Airport (AZA) is at around 7:00AM UTC-7. Board this plane and you’ll touch down at Sioux Falls Regional Airport (FSD) at approximately 10:50AM UTC-6. The overall travel time is 2h 50m.
How long does it take to fly from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD)?
It usually takes 2 hours and 50 minutes to travel the 1,050 mi from AZA to FSD.
What is the best time to fly from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD)?
Opt for a flight from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Sioux Falls from Phoenix - Mesa Gateway Airport (AZA)?
Browse your flight options from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD). This is the only Sioux Falls airport you can touch down at if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD) last-minute?
Booking your flight from AZA to FSD just before your journey is generally more expensive. But if there’s some wiggle room with your departure dates and times, you could land a cheap last-minute fare.
Is it cheaper to book an AZA to FSD flight and hotel package?
Opting for an AZA to FSD flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Pick from our wide range of accommodations and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Phoenix - Mesa Gateway Airport (AZA) to Sioux Falls Regional Airport (FSD)?
In most instances, you can reschedule or cancel your AZA to FSD flight. However, there may be additional charges, especially if you made your booking over 24 hours ago. Check your itinerary for the airline’s fees and policies on flight changes, or if you want more details, head to our Customer Service portal.

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*Available to One Key members.