Cheap Flights from Mesa (AZA) to Des Moines (DSM)

Popular airlines from Phoenix - Mesa Gateway Airport (AZA) to Des Moines International Airport (DSM)

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Flights from Mesa (AZA) to Des Moines (DSM)
Origin airport
Phoenix - Mesa Gateway
Destination airport
Des Moines Intl.
Distance
1137 mi

Mesa to Des Moines Flights

The cheapest times to fly from Mesa to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mesa to Des Moines are during the month of . You can find some of the cheapest flights from Mesa to Des Moines with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Mesa to Des Moines

Sunday is one of the best days to book for cheap flights from Mesa to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Mesa to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mesa to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mesa to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mesa to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM) cost?
Discover the latest flight deals from AZA to DSM by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from AZA to DSM?
The cheapest flights from AZA to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM)?
Although Mesa, AZ (AZA-Phoenix - Mesa Gateway) has no direct flights to Des Moines Intl. Airport (DSM), other airports have nonstop options. Traveling from Sky Harbor Intl. Airport (PHX) will get you to Des Moines without any detours.
What is the cheapest airline that flies from AZA to DSM?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from AZA to DSM. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM)?
On average, you can take your pick of 4 nonstop flights departing from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM) weekly. If you don’t see one that fits your schedule, consider taking a flight that includes a layover. Filter your search results on Expedia to include one or two stops and opt for the next best option.
What are the most popular departure times for flights from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM)?
Flights between AZA and DSM are their busiest at 1 PM. For a more relaxed atmosphere and possibly cheaper tickets, look for a departure that’s outside typical rush times.
What day of the week has the most flights from AZA to DSM?
Travel on a Friday if you’re searching for the best selection of flights from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM).
What is the earliest flight from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM)?
Phoenix - Mesa Gateway Airport (AZA)’s earliest flight to Des Moines Intl. Airport (DSM) is at approximately 1:08PM UTC-7. With a travel duration of 2h 49m, you’ll land at around 4:57PM UTC-6.
How long does it take to fly from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM)?
Flights from AZA to DSM have an average travel time of 2 hours and 49 minutes. The distance between the two airports is 1,150 mi.
What is the best time to fly from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM)?
To avoid possible delays on the Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM) route, travel before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Des Moines from Phoenix - Mesa Gateway Airport (AZA)?
Browse your flight options from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM). This is the only Des Moines airport you can arrive at if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM) last-minute?
Booking your ticket from AZA to DSM shortly before your trip is generally more expensive. However, if you’re flexible with your travel dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book an AZA to DSM flight and hotel package?
You can save money by securing an AZA to DSM flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage everything in one place. After choosing your ideal flights and accommodations, you can add extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from Phoenix - Mesa Gateway Airport (AZA) to Des Moines Intl. Airport (DSM)?
If you booked your AZA to DSM flight in the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

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*Available to One Key members.