$438 Cheap Flights from Amsterdam (AMS) to Panama City (PTY)

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Find available prices by choosing your travel dates.

Cheap Flights from Amsterdam to Panama City (AMS-PTY)

Prices were available within the past 7 days and start at $438 for one-way flights and $648 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

FlexFlight
United
Lufthansa
United
Swiss International Air Lines
Lufthansa
United
Austrian Airlines
Air Canada
United
Flights from Amsterdam (ZYA) to Panama City (PTY)
Origin airport
Amsterdam Central Station
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, Air Europa, Air France, American Airlines, British Airways, Delta, Iberia, KLM, Turkish Airlines, United
Roundtrip price
$647
Distance
5482 mi

Amsterdam to Panama City Flights

The cheapest times to fly from Amsterdam to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Amsterdam to Panama City are during the month of June. You can find some of the cheapest flights from Amsterdam to Panama City with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Amsterdam to Panama City

Sunday is one of the best days to book for cheap flights from Amsterdam to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Amsterdam to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Amsterdam to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $438 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Amsterdam to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Amsterdam to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How long does it take to fly from Schiphol Airport (AMS) to Panama Airport?
Book a trip with KLM and you can expect to be traveling for approximately 10 hours and 50 minutes. This popular carrier has a direct flight that jets off at 1:00PM from Schiphol Airport (AMS) and arrives at Panama Airport at 4:50PM. Expedia has some of the best deals around, so find out what’s on offer on this route today.
Is it cheaper to buy a plane ticket from Amsterdam Airport Schiphol to PTY last minute?
When it comes to booking your flights, it pays to be prepared. While you could pick up a deal on a Schiphol Airport (AMS) to PTY flight at the last minute, tickets usually don’t get cheaper as the departure date nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to book a domestic flight is between 28 – 35 days in advance. For international journeys it’s three to four months.
What airline has the least delays from Amsterdam Airport Schiphol to PTY?
With an on-time flight record of 75%, KLM is the airline that’s more likely to get you from AMS to PTY without any interruptions. Flight delays can be an excuse to head to the airport bar. However, they can also cause you to miss a vital connection that could ruin your entire vacation. You can stay updated about delays by reviewing your flight status through the Expedia App long before you get to the airport. If you’re already at your gate and you’re worried about how the disruption will affect your trip, visit the customer service desk to find out what your options are.
What airports do you fly into for Panama City from Amsterdam?
From Amsterdam, you can get to Panama City via Tocumen Intl. Airport (PTY), Marcos A. Gelabert Intl. Airport (PAC) and Panama Pacifico Intl. Airport (BLB). Be sure to check which hub is the most convenient for you before making your decision. If you go with Tocumen Intl. Airport (PTY), it’s approximately 11 mi northeast of the city center. Use the dollars you save when booking your airfare with Expedia to enjoy the city’s popular sights, such as Miraflores Locks and Metropolitan Cathedral of Panama.
What are the most popular departure times for flights from Amsterdam Airport Schiphol to PTY?
For KLM flights jetting from Amsterdam Airport Schiphol to Panama Airport, the peak period is between 12:00 PM - 1:00 PM. If you’d like to avoid any delays, book the earliest flight. This gives you a better chance to avoid air traffic that builds up around airports later in the day.
Can I change the date of my flight from AMS to Panama Airport?
Plans can change, so Expedia is here to help make things easier. To start, find your AMS to Panama Airport itinerary through the Expedia Trips portal and check the ticket rules about what changes you can make. If you purchased your ticket in the last 24 hours, some carriers will let you cancel for free and book new flights. If you bought your ticket more than 24 hours ago, contact us through our Customer Service portal to find out what your options are.

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*Available to One Key members.