$129 Cheap Flights from Amarillo (AMA) to San Diego (SAN)

View $129 flight on Fri, Jun 27, 2025Opens in a new window

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.

Cheap Flights from Amarillo to San Diego (AMA-SAN)

Prices were available within the past 7 days and start at $129 for one-way flights and $257 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Wed, Jul 23 - Fri, Aug 8
AMA
Amarillo
SAN
San Diego
$257 Roundtrip, found 6 hours ago
$257
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Wed, Jul 23 from Amarillo to San Diego, returning Fri, Aug 8, priced at $257 found 6 hours ago
United
Wed, Jul 2 - Thu, Jul 17
AMA
Amarillo
SAN
San Diego
$261 Roundtrip, found 6 hours ago
$261
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Jul 2 from Amarillo to San Diego, returning Thu, Jul 17, priced at $261 found 6 hours ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
AMA
Amarillo
CLD
Carlsbad
$267 Roundtrip, found 1 day ago
$267
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 16 from Amarillo to Carlsbad, returning Fri, Jun 20, priced at $267 found 1 day ago
United
Fri, Jun 20 - Wed, Jun 25
AMA
Amarillo
SAN
San Diego
$273 Roundtrip, found 9 hours ago
$273
Roundtrip
found 9 hours ago
Select United flight, departing Fri, Jun 20 from Amarillo to San Diego, returning Wed, Jun 25, priced at $273 found 9 hours ago
United
Fri, Jul 11 - Tue, Jul 15
AMA
Amarillo
SAN
San Diego
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select United flight, departing Fri, Jul 11 from Amarillo to San Diego, returning Tue, Jul 15, priced at $279 found 1 day ago
United
Tue, Jun 3 - Tue, Jun 10
AMA
Amarillo
SAN
San Diego
$284 Roundtrip, found 7 hours ago
$284
Roundtrip
found 7 hours ago
Select United flight, departing Tue, Jun 3 from Amarillo to San Diego, returning Tue, Jun 10, priced at $284 found 7 hours ago
Southwest Airlines
Tue, Jun 3 - Tue, Jun 10
AMA
Amarillo
SAN
San Diego
$285 Roundtrip, found 7 hours ago
$285
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Tue, Jun 3 from Amarillo to San Diego, returning Tue, Jun 10, priced at $285 found 7 hours ago
American Airlines
Mon, Oct 6 - Wed, Oct 15
AMA
Amarillo
SAN
San Diego
$287 Roundtrip, found 3 days ago
$287
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Oct 6 from Amarillo to San Diego, returning Wed, Oct 15, priced at $287 found 3 days ago
United
Sat, Jun 7 - Tue, Jun 10
AMA
Amarillo
SAN
San Diego
$288 Roundtrip, found 5 days ago
$288
Roundtrip
found 5 days ago
Select United flight, departing Sat, Jun 7 from Amarillo to San Diego, returning Tue, Jun 10, priced at $288 found 5 days ago
American Airlines
Tue, Jun 3 - Tue, Jun 10
AMA
Amarillo
SAN
San Diego
$291 Roundtrip, found 7 hours ago
$291
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Jun 3 from Amarillo to San Diego, returning Tue, Jun 10, priced at $291 found 7 hours ago
Flights from Amarillo (AMA) to San Diego (SAN)
Origin airport
Rick Husband Amarillo Intl.
Destination airport
San Diego Intl.
Airlines serving
American Airlines, Southwest Airlines, United
Roundtrip price
$256
Distance
903 mi

Amarillo to San Diego Flights

The cheapest times to fly from Amarillo to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Amarillo to San Diego are during the month of July. You can find some of the cheapest flights from Amarillo to San Diego with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Amarillo to San Diego

Sunday is one of the best days to book for cheap flights from Amarillo to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Amarillo to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Amarillo to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from $129 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Amarillo to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Amarillo to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Rick Husband Amarillo Intl. Airport (AMA) to San Diego Intl. Airport (SAN) cost?
Discover the latest flight deals from AMA to SAN by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from AMA to SAN?
The cheapest flights from AMA to SAN are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from AMA to SAN?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from AMA to SAN. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Rick Husband Amarillo Intl. Airport (AMA) to San Diego Intl. Airport (SAN)?
Direct flights from Rick Husband Amarillo Intl. Airport (AMA) to San Diego Intl. Airport (SAN) aren’t available daily, so you’ll need to take a flight with a layover. Explore your options with Expedia’s filters. Enter your travel dates and choose either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from AMA to SAN?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary depending on a number of factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Rick Husband Amarillo Intl. Airport (AMA) to San Diego Intl. Airport (SAN)?
To arrive at San Diego Intl. Airport (SAN) without delays, book a flight that leaves Rick Husband Amarillo Intl. Airport (AMA) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Rick Husband Amarillo Intl. Airport (AMA) to San Diego Intl. Airport (SAN) last-minute?
Booking your flight from AMA to SAN right before your trip is typically more expensive. However, if you’re flexible with your schedule, you could bag a cheap last-minute fare.
Is it cheaper to book an AMA to SAN flight and hotel package?
Securing an AMA to SAN flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our extensive range of stays and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rick Husband Amarillo Intl. Airport (AMA) to San Diego Intl. Airport (SAN)?
In most instances, you’re able to reschedule or cancel your AMA to SAN flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline’s rules and fees on flight changes, or if you need further information, visit our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.