$110 Cheap Delta flights Missoula (MSO) to San Francisco (SFO)

Finding cheap one-way Delta Air Lines flights from MSO to SFO from $110 on Expedia couldn’t be easier — just filter by “Price (lowest to highest).” Alternatively, check out our affordable return fares from $219 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for one-way or round-trip flights to San Francisco in February or April. You could find lower fares with Delta Air Lines during these off-peak times.

Look for affordable Delta Air Lines flights from Missoula Intl. Airport (MSO) to San Francisco Intl. Airport (SFO) one to three months ahead of your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and journey, the best day to book a domestic flight is generally Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use our “Nonstop” filter when browsing for direct Delta Air Lines flights from MSO to SFO. It’s also a great way to compare other carriers servicing the same direct route.

Filter your results by “Early Morning” and “Morning” to browse the earliest departures from MSO to SFO. Taking off early means you’re less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Take a Delta Air Lines flight from Missoula Intl. Airport (MSO) to San Francisco, and you’re most likely to land at San Francisco Intl. Airport (SFO). This is the airline’s main hub in this destination.

Traveling from MSO to SFO with Delta Air Lines means enjoying a host of perks, including a rewarding loyalty program and an excellent in-flight experience. Plus, when you book through Expedia, One Key™ members can collect OneKeyCash™* to redeem on select future travel purchases. That’s in addition to the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Changes are often free within 24 hours of booking, but your airline may add a charge after that. For more details about modifying your reservation, check out your “Trips,” select your flight and click on “Manage Booking.” If you’d like the flexibility to change your itinerary without additional charges, check the “No cancel fee” or “Changes included” filter when organizing your next trip.