
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Find available prices by choosing your travel dates.
$201 Cheap Delta flights Knoxville (TYS) to Detroit (DTW)
Prices were available within the past 7 days and start at $201 for one-way flights and $353 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, May 28 - Wed, Jun 11
TYS
Knoxville
DTW
Detroit
$353 Roundtrip, found 7 hours ago
$353
Roundtrip
found 7 hours ago

Wed, Jun 18 - Sat, Jul 5
TYS
Knoxville
DTW
Detroit
$366 Roundtrip, found 21 hours ago
$366
Roundtrip
found 21 hours ago

Tue, May 27 - Tue, Jun 3
TYS
Knoxville
DTW
Detroit
$368 Roundtrip, found 3 days ago
$368
Roundtrip
found 3 days ago

Thu, May 29 - Sun, Jun 1
TYS
Knoxville
DTW
Detroit
$370 Roundtrip, just found
$370
Roundtrip
just found

Wed, May 28 - Mon, Jun 9
TYS
Knoxville
DTW
Detroit
$376 Roundtrip, found 7 hours ago
$376
Roundtrip
found 7 hours ago

Thu, Jul 3 - Sun, Jul 6
TYS
Knoxville
DTW
Detroit
$399 Roundtrip, just found
$399
Roundtrip
just found
Origin airport | McGhee Tyson |
Destination airport | Detroit Metropolitan Wayne County |
Airlines serving | American Airlines, Delta, Frontier Airlines, United |
Popular airline | American Airlines |
Distance | 444 mi |
Frequently asked questions
Explore a world of travel with Expedia
Flights
- Delta Knoxville (TYS) to Las Vegas (LAS) flights
- Delta Knoxville (TYS) to Miami (MIA) flights
- Delta Detroit (DTW) to Tampa (TPA) flights
- Delta Detroit (DTW) to Newark Liberty Intl. Airport (EWR) flights
- Delta Knoxville (TYS) to Newark Liberty Intl. Airport (EWR) flights
- Delta Knoxville (TYS) to Chicago (ORD) flights
- Delta Knoxville (TYS) to Orlando (MCO) flights
- Delta Detroit (DTW) to Los Angeles (LAX) flights
- Delta Knoxville (TYS) to Dallas (DFW) flights
- Delta Detroit (DTW) to Fort Lauderdale (FLL) flights
- Delta Knoxville (TYS) to Houston (IAH) flights
- Delta Knoxville (TYS) to New York (LGA) flights
- Delta Detroit (DTW) to Fort Myers (RSW) flights
- Delta Knoxville (TYS) to New York (JFK) flights
- Delta Detroit (DTW) to San Diego (SAN) flights
- Delta Detroit (DTW) to New Orleans (MSY) flights
- Delta Knoxville (TYS) to Denver (DEN) flights
- Delta Detroit (DTW) to Denver (DEN) flights
- Delta Detroit (DTW) to Punta Cana (PUJ) flights
- Delta Detroit (DTW) to Phoenix (PHX) flights
- Aer Lingus
- Virgin Atlantic
- British Airways
- United
- Frontier Airlines
- Lufthansa
- Aeromexico
- Air France
- American Airlines
- Brussels Airlines
- Alaska Airlines
- Air Canada
- Delta
- KLM
- Qatar Airways
- Finnair
- Flights from North Carolina Mountains
- Flights from Gatlinburg - Pigeon Forge
- Flights from Gatlinburg
- Flights from Maryville
- Flights from Pigeon Forge
- Flights from Kodak
- Flights from La Follette
- Flights from Wears Valley
- Flights from Knoxville
- Flights from Blue Ridge Mountains
- Flights from Townsend
- Flights from Sevierville
- Flights from DeKalb-Peachtree
- Flights from Virginia Highlands
- Flights from Pike County - Hatcher Field
- Flights from Tri-Cities Regional
- Flights from Asheville Regional
- Flights from Smyrna
- Flights from Greenville-Spartanburg Intl.
- Flights from Fulton County
- Flights from Nashville Intl.
- Flights from Chattanooga Metropolitan
- Flights from Nashville (BNA) to Las Vegas (LAS)
- Flights from Memphis (MEM) to Las Vegas (LAS)
- Flights from Memphis (MEM) to Miami (MIA)
- Flights from New York (JFK) to Miami (MIA)
- Flights from New York (LGA) to Miami (MIA)
- Flights from Los Angeles (LAX) to San Salvador (SAL)
- Flights from Nashville (BNA) to Seattle (SEA)
- Flights from Los Angeles (LAX) to Honolulu (HNL)
- Flights from Nashville (BNA) to Chicago (ORD)
- Flights from Memphis (MEM) to Chicago (ORD)
- Flights from Grand Rapids (GRR) to Orlando (MCO)
- Flights from Nashville (BNA) to Orlando (MCO)
- Flights from Memphis (MEM) to Orlando (MCO)
- Flights from Boston (BOS) to Orlando (MCO)
- Flights from Newark Liberty Intl. Airport (EWR) to Orlando (MCO)
- Flights from New York (JFK) to Orlando (MCO)
- Flights from Nashville (BNA) to Los Angeles (LAX)
- Flights from Nashville (BNA) to Dallas (DFW)
- Flights from Memphis (MEM) to Dallas (DFW)
- Flights from Nashville (BNA) to New York (JFK)
- Flights from Los Angeles (LAX) to New York (JFK)
- Flights from Los Angeles (LAX) to Tokyo (HND)
- Flights from Los Angeles (LAX) to San José del Cabo (SJD)
- Flights from New York (JFK) to Santo Domingo (SDQ)
- Flights from Raleigh (RDU) to Nashville (BNA)
- Flights from Denver (DEN) to Nashville (BNA)
- Flights from New York (LGA) to Nashville (BNA)
- Flights from Newark Liberty Intl. Airport (EWR) to Nashville (BNA)
- Flights from Chicago (ORD) to Nashville (BNA)
- Flights from Phoenix (PHX) to Nashville (BNA)
- Flights from Los Angeles (LAX) to Nashville (BNA)
- Flights from Philadelphia (PHL) to Nashville (BNA)
- Flights from Seattle (SEA) to Nashville (BNA)
- Flights from Houston (IAH) to Nashville (BNA)
- Flights from Orlando (MCO) to Nashville (BNA)
- Flights from Minneapolis (MSP) to Nashville (BNA)
- Flights from Tampa (TPA) to Nashville (BNA)
- Flights from Detroit (DTW) to Nashville (BNA)
- Flights from Boston (BOS) to Nashville (BNA)
- Flights from Dallas (DFW) to Nashville (BNA)
- Flights from Nashville (BNA) to Denver (DEN)
- Flights from Chicago (ORD) to Cancun (CUN)
- Flights from New York (JFK) to Cancun (CUN)
- Flights from Dallas (DAL) to Cancun (CUN)
*Available to One Key members.