$148 Cheap Delta flights Los Angeles (LAX) to Des Moines (DSM)

Apply the “Price (lowest to highest)” filter on Expedia to find cheap Delta Air Lines round-trip flights from $295 from LAX to DSM. Affordable one-way tickets from $148 are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Delta Air Lines flights to Des Moines are usually cheaper in the off-peak months of January and December. Whether you need a round-trip or one-way ticket, you could score a better deal then.

Begin your search one to three months ahead of your travel date to score cheaper fares on Delta Air Lines flights from Los Angeles Intl. Airport (LAX) to Des Moines Intl. Airport (DSM). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use our “Nonstop” filter when looking for direct Delta Air Lines flights from LAX to DSM. It’s also a good way to compare other carriers servicing the same direct trip.

Sort your results by “Morning” and “Early Morning” to see the earliest flights from LAX to DSM. Leaving early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Des Moines Intl. Airport (DSM) is the main Des Moines gateway for Delta Air Lines flights from Los Angeles Intl. Airport (LAX).

Heading from LAX to DSM with Delta Air Lines means enjoying a range of perks, such as a rewarding loyalty program and an excellent in-flight experience. Plus, when booking through Expedia, One Key™ members can earn OneKeyCash™* to use on select future travel purchases. That’s on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

In most cases, you can cancel or modify your flight, although there may be additional charges if you booked more than 24 hours ago. Need to keep your options open? Use our “Changes included” or “No cancel fee” filter to find flights that won’t penalize you if you have to adjust your plans. To update your itinerary, visit “Trips,” select your flight and click on “Manage Booking” for more details.