$144 Cheap Delta flights St. Louis (STL) to Panama City (ECP)

Use the “Price (lowest to highest)” filter on Expedia to find cheap Delta Air Lines round-trip flights from $252 from STL to ECP. Affordable one-way fares from $144 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Delta Air Lines flights to Panama City are often cheaper in the off-peak months of November and February. Whether you need a one-way or round-trip ticket, you could find a better deal then.

Search for cheap Delta Air Lines flights from Lambert-St. Louis Intl. Airport (STL) to Northwest Florida Beaches Intl. Airport (ECP) one to three months before your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day of the week to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on our “Nonstop” filter when searching for direct Delta Air Lines flights from STL to ECP. You’ll also be able to compare other carriers offering the same nonstop trip.

To find the earliest departure from STL to ECP with Delta Air Lines, filter your search by “Early Morning” and “Morning.” Booking an early flight usually means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Northwest Florida Beaches Intl. Airport (ECP) is the primary Panama City hub for Delta Air Lines flights from Lambert-St. Louis Intl. Airport (STL).

Heading from STL to ECP with Delta Air Lines means enjoying a range of perks, including an excellent in-flight experience and a rewarding loyalty program. Plus, when you book through Expedia, One Key™ members can collect OneKeyCash™* to spend on select future travel purchases. That’s on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Changes are often free within 24 hours of making your booking, but your airline may charge a fee after that time. For further details about altering your reservation, check out your “Trips,” select your flight and click on “Manage Booking.” If you’d like the freedom to make changes without additional charges, check the “No cancel fee” or “Changes included” filter when organizing your next getaway.