$139 Cheap Delta flights Orange County (SNA) to Knoxville (TYS)

Make use of the “Price (lowest to highest)” filter on Expedia to look for cheap Delta Air Lines return flights from $277 from SNA to TYS. Affordable one-way fares from $139 are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the cheapest months to jet away to Knoxville with Delta Air Lines. You could also find excellent prices on return and one-way fares in December.

Begin your search one to three months before your departure to score cheap fares on Delta Air Lines flights from John Wayne Airport (SNA) to McGhee Tyson Airport (TYS). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Nail your timing, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on our “Nonstop” filter when looking for direct Delta Air Lines flights from SNA to TYS. You’ll also be able to compare other airlines offering the same nonstop journey.

Sort your results by “Morning” and “Early Morning” to find the earliest flights from SNA to TYS. Heading off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Delta Air Lines flights from John Wayne Airport (SNA) to Knoxville arrive at McGhee Tyson Airport (TYS). This is the main entry point to this destination.

Offering an excellent in-flight experience and a rewarding loyalty program, Delta Air Lines is the leading choice for many passengers flying from SNA to TYS. Also, if you’re a Delta SkyMiles and One Key™ member booking with Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can go toward future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Depending on the ticket type you purchased, a fee may apply if you cancel or reschedule your booking more than 24 hours after confirmation. To secure flexible plane tickets, select our “Changes included” and “No cancel fee” boxes when looking for flights. For more information on modifying or canceling your reservation, visit “Trips,” select your flight and tick “Manage Booking.”