$132 Cheap Delta flights Des Moines (DSM) to Chicago (ORD)

You’ll find cheap return Delta Air Lines flights from $209 from DSM to ORD by sorting your results from “Price (lowest to highest)” on Expedia. Or search for options from $132 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Delta Air Lines flights to Chicago are generally more affordable in the off-peak months of January and February. Whether you’re searching for a one-way or a return ticket, you could score a better deal then.

For cheap Delta Air Lines fares from Des Moines Intl. Airport (DSM) to O’Hare Intl. Airport (ORD), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact how much you pay. Sunday is usually the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by choosing to book on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To see if there’s a direct journey from DSM to ORD with Delta Air Lines or another carrier, check the “Nonstop” filter when looking for flights.

Find Delta Air Lines’s earliest flights from DSM to ORD by using our “Morning” and “Early Morning” filters. Not only will you get to your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Take a Delta Air Lines flight from Des Moines Intl. Airport (DSM) to Chicago, and you’ll probably arrive at O’Hare Intl. Airport (ORD). This is the airline’s main hub in this destination.

With an excellent in-flight experience and a rewarding loyalty program, Delta Air Lines is a popular option for many passengers heading from DSM to ORD. What’s more, if you’re a Delta SkyMiles and One Key™ member booking through Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can be spent on future getaways.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Typically, you can reschedule or cancel your flight, although there may be additional fees if you booked more than 24 hours ago. Need to keep your options open? Use our “No cancel fee” or “Changes included” filter to find flights that won’t charge you extra if you have to adjust your plans. To make modifications, go to “Trips,” select your flight and click on “Manage Booking” for more details.