$216 Cheap American Airlines flights Tampa (TPA) to Panama City (PTY)

Grab budget-friendly return American Airlines flights from $202 from TPA to PTY by organizing your results from “Price (lowest to highest)” on Expedia. Or look for deals from $216 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

November is one of the cheapest months to travel to Panama City with American Airlines. You could also find great prices on one-way and return fares in September.

Snagging the best American Airlines deals from TPA to PTY often comes down to booking at the right moment. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. Better yet, you can pocket 17% on average by buying your tickets on a Sunday rather than a Friday, which is often the most expensive day to book.* It’s a good idea to start searching for flights about one month before your travel dates.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on our “Nonstop” filter when looking for direct American Airlines flights from TPA to PTY. It’s also a great way to compare other carriers offering the same nonstop journey.

Browse American Airlines’s earliest flights from TPA to PTY by selecting the “Morning” and “Early Morning” filters. Not only will you arrive sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Tampa Intl. Airport (TPA) to Panama City arrive at Tocumen Intl. Airport (PTY). This is the main gateway here.

Changes are generally free within 24 hours of making your booking, but your airline may add a charge after that. For more details about modifying your flights, go to your “Trips,” select your flight and click on “Manage Booking.” If you want the freedom to update your itinerary without extra charges, apply the “Changes included” and “No cancel fee” filters when planning your next adventure.