$119 Cheap American Airlines flights Chicago (ORD) to San Diego (SAN)

Set the “Price (lowest to highest)” filter on Expedia to look for cheap American Airlines return flights from $166 from ORD to SAN. Affordable one-way tickets from $119 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to San Diego are usually more affordable in the low-season months of January and November. Whether you need a one-way or round-trip ticket, you could land a better deal then.

For cheap American Airlines fares from O’Hare Intl. Airport (ORD) to San Diego Intl. Airport (SAN), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect how much you pay. Sunday is typically the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by choosing to book on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

American Airlines offers direct flights from O’Hare Intl. Airport (ORD) to San Diego Intl. Airport (SAN), with 14 weekly departures. Just choose the “Nonstop” and “Airline” filters while searching on Expedia to show all direct American Airlines flights to SAN.

Take off from O’Hare Intl. Airport (ORD) for San Diego Intl. Airport (SAN) on a direct American Airlines flight, and you’ll be in the sky for about 4h 27m.

American Airlines has the most flights from O’Hare Intl. Airport (ORD) to San Diego Intl. Airport (SAN) on Tuesday. With up to 2 daily departures, you’ll get the most flexibility on this day.

The first American Airlines flight from ORD to SAN departs at 10:05AM UTC-6, landing at 12:36PM UTC-8. If you prefer to set off later, the last American Airlines flight leaves ORD at 5:45PM UTC-6 and touches down at SAN at 8:10PM UTC-8. Flying before noon is often a smart option as morning and mid-morning flights tend to experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from O’Hare Intl. Airport (ORD) to San Diego land at San Diego Intl. Airport (SAN). This is the main gateway to this destination.

For the O’Hare Intl. Airport (ORD) to San Diego Intl. Airport (SAN) route, American Airlines typically flies Airbus A321 and Boeing 737-800 planes. Remember that last-minute changes can occur for operational needs, meaning your flight may be on a different aircraft.

Typically, you can cancel or modify your flight, although additional fees may apply if your booking was made over 24 hours ago. Prefer to keep your options open? Use our “Changes included” or “No cancel fee” filter to find flights that won’t penalize you if you have to alter your plans. To modify your booking, go to “Trips,” select your flight and click on “Manage Booking” for further information.