$121 Cheap American Airlines flights Newark Liberty Intl. Airport (EWR) to St. Louis (STL)

Set the “Price (lowest to highest)” filter on Expedia to find cheap American Airlines return flights from $241 from EWR to STL. Affordable one-way fares from $121 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the cheapest months to jet away to St. Louis with American Airlines. You could also find fantastic deals on one-way and round-trip fares in February.

Start searching one to three months ahead of your departure date to find cheap fares on American Airlines flights from Liberty Intl. Airport (EWR) to Lambert-St. Louis Intl. Airport (STL). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Time it well, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To figure out if there’s a direct journey from EWR to STL with American Airlines or any other carriers, check the “Nonstop” filter when browsing for tickets.

Browse American Airlines’s earliest flights from EWR to STL by selecting the “Early Morning” and “Morning” filters. Not only will you arrive at your destination sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Jump on an American Airlines flight from Liberty Intl. Airport (EWR) to St. Louis, and you’ll likely land at Lambert-St. Louis Intl. Airport (STL). This is the airline’s main hub in this destination.

Changes are often free within 24 hours of making a booking, but your airline may add a charge after that time. For more details about altering your reservation, go to your “Trips,” select your flight and click on “Manage Booking.” If you want the freedom to make changes without additional charges, apply the “Changes included” and “No cancel fee” filters when planning your next trip.