$100 Cheap American Airlines flights Minneapolis (MSP) to Lexington (LEX)

Finding cheap one-way American Airlines flights from MSP to LEX from $100 on Expedia is simple — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly return fares from $219 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to get away to Lexington with American Airlines. You could also find excellent prices on one-way and return fares in February.

Start searching one to three months ahead of your departure date to score cheaper fares on American Airlines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Blue Grass Airport (LEX). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use the “Nonstop” filter when looking for direct American Airlines flights from MSP to LEX. It’s also a good way to compare other carriers servicing the same nonstop trip.

Filter your results by “Morning” and “Early Morning” to browse the earliest departures from MSP to LEX. Taking off early means you’re less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Lexington land at Blue Grass Airport (LEX). This is the main gateway to this destination.

Depending on the type of fare you purchased, a fee may apply if you modify or cancel your booking more than 24 hours after it has been confirmed. To find plane tickets with more flexibility, select our “Changes included” or “No cancel fee” filter while looking for flights. For more information on changing or canceling your reservation, visit “Trips,” select your flight and tick “Manage Booking.”