$379 Cheap American Airlines flights Knoxville (TYS) to Honolulu (HNL)

Landing cheap one-way American Airlines flights from TYS to HNL from $379 on Expedia couldn’t be easier — just filter by “Price (lowest to highest).” Or check out our affordable round-trip fares from $807 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

November is one of the least expensive months to jet off to Honolulu with American Airlines. You could also find fantastic deals on one-way and return tickets in October.

Look for affordable American Airlines flights from McGhee Tyson Airport (TYS) to Daniel K. Inouye Intl. Airport (HNL) one to three months before your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and itinerary, the best day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on the “Nonstop” filter when browsing for direct American Airlines flights from TYS to HNL. You’ll also be able to compare other carriers servicing the same direct route.

Browse American Airlines’s earliest flights from TYS to HNL by selecting our “Morning” and “Early Morning” filters. Not only will you arrive at your destination sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Daniel K. Inouye Intl. Airport (HNL) is the primary Honolulu hub for American Airlines flights from McGhee Tyson Airport (TYS).

In most cases, you can reschedule or cancel your flight, although additional fees may apply if you booked more than 24 hours ago. Need flexible options? Make use of Expedia’s “Changes included” and “No cancel fee” filters to find flights that won’t charge you extra if you need to adjust your plans. To update your itinerary, go to “Trips,” select your flight and click on “Manage Booking” for further information.