$136 Cheap American Airlines flights Manchester (MHT) to Greenville (GSP)

Grab affordable return American Airlines flights from $271 from MHT to GSP by organizing your results from “Price (lowest to highest)” on Expedia. Or search for bargains from $136 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Browse for one-way or round-trip flights to Greenville in January or December. You could find lower fares with American Airlines during these off-peak months.

Begin your search one to three months ahead of your travel date to score cheap fares on American Airlines flights from Manchester-Boston Regional Airport (MHT) to Greenville-Spartanburg Intl. Airport (GSP). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Simply enter your dates, hit search and use the “Nonstop” filter on Expedia to browse any direct flights from MHT to GSP with American Airlines or another carrier.

Filter your results by “Early Morning” and “Morning” to see the earliest departures from MHT to GSP. Leaving early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Manchester-Boston Regional Airport (MHT) to Greenville come in to land at Greenville-Spartanburg Intl. Airport (GSP). This is the main gateway here.

Changes are usually free within 24 hours of making your booking, but your airline may charge a fee after that. For more information about altering your flights, head to your “Trips,” select your flight and click on “Manage Booking.” If you’d like the freedom to change your itinerary without extra charges, apply the “Changes included” and “No cancel fee” filters when planning your next escape.