$129 Cheap American Airlines flights Boston (BOS) to San Francisco (SFO)

You’ll discover affordable return American Airlines flights from $257 from BOS to SFO by filtering your results from “Price (lowest to highest)” on Expedia. Or search for deals from $129 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to San Francisco are generally more affordable in the quieter months of February and April. Whether you’re in search of a one-way or round-trip ticket, you could find a better deal then.

Look for affordable American Airlines flights from Logan Intl. Airport (BOS) to San Francisco Intl. Airport (SFO) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and journey, the best day of the week to book a domestic flight is usually Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use our “Nonstop” filter when searching for direct American Airlines flights from BOS to SFO. It’s also a good way to compare other airlines offering the same direct route.

Filter your results by “Morning” and “Early Morning” to see the earliest flights from BOS to SFO. Setting off early means you’re less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

San Francisco Intl. Airport (SFO) is the primary San Francisco hub for American Airlines flights from Logan Intl. Airport (BOS).

It’s usually possible to reschedule or cancel your flight, although additional fees may apply if your booking was made over 24 hours ago. Want to keep your options open? Make use of our “No cancel fee” and “Changes included” filters to find flights that won’t penalize you if you have to adjust your plans. To update your booking, go to “Trips,” select your flight and click on “Manage Booking” for further information.