$109 Cheap American Airlines flights New York (LGA) to San Diego (SAN)

You’ll find affordable round-trip American Airlines flights from $217 from LGA to SAN by filtering your results from “Price (lowest to highest)” on Expedia. Or look for bargains from $109 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for one-way or return flights to San Diego in January or November. You could find lower fares with American Airlines during these off-season months.

Look for affordable American Airlines flights from LaGuardia Airport (LGA) to San Diego Intl. Airport (SAN) one to three months prior to your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and journey, the best day of the week to book a domestic flight is generally Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To find out if there’s a direct route from LGA to SAN with American Airlines or another airline, use our “Nonstop” filter when searching for tickets.

Filter your results by “Early Morning” and “Morning” to see the earliest departures from LGA to SAN. Setting off early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

San Diego Intl. Airport (SAN) is the main San Diego hub for American Airlines flights from LaGuardia Airport (LGA).

It’s usually possible to modify or cancel your flight, although there may be additional fees if you booked more than 24 hours ago. Prefer to keep your options open? Make use of Expedia’s “Changes included” and “No cancel fee” filters to find flights that won’t charge you extra if you need to adjust your plans. To update your booking, go to “Trips,” select your flight and click on “Manage Booking” for more information.