$111 Cheap American Airlines flights New York (LGA) to St. Louis (STL)

Scoring cheap one-way American Airlines flights from LGA to STL from $111 on Expedia is easy — just filter by “Price (lowest to highest).” Alternatively, check out our affordable return fares from $219 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to St. Louis are generally cheaper in the low-season months of January and February. Whether you’re searching for a one-way or a return ticket, you could find a better deal then.

Start searching one to three months ahead of your departure date to score cheaper fares on American Airlines flights from LaGuardia Airport (LGA) to Lambert-St. Louis Intl. Airport (STL). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing right, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

You can easily fly from LaGuardia Airport (LGA) to Lambert-St. Louis Intl. Airport (STL) on any of American Airlines’s 19 direct weekly flights. Apply our “Nonstop” and “Airline” filters to find the American Airlines flight that’ll arrive at STL at a time that suits you.

It takes around 3h 2m to fly nonstop from LaGuardia Airport (LGA) to Lambert-St. Louis Intl. Airport (STL) with American Airlines.

Thursday has the most American Airlines flights from LaGuardia Airport (LGA) to Lambert-St. Louis Intl. Airport (STL). With 3 daily departures, this is a great day to book something that will suit your plans.

The first American Airlines flight from LGA to STL departs at 9:30AM UTC-5, arriving at 11:32AM UTC-6. If you prefer to jet off later in the day, the last American Airlines flight leaves LGA at 6:05PM UTC-5 and lands at STL at 8:09PM UTC-6. Flying before noon is generally a wise choice as morning and mid-morning flights are less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from LaGuardia Airport (LGA) to St. Louis touch down at Lambert-St. Louis Intl. Airport (STL). This is the main entry point here.

You’ll most likely be on an Embraer 175 for your American Airlines flight from LaGuardia Airport (LGA) to Lambert-St. Louis Intl. Airport (STL). However, you may end up on another aircraft if there are operational changes.

You can usually reschedule or cancel your flight, although there may be additional fees if you made your booking more than 24 hours ago. Need to keep your options open? Use our “Changes included” and “No cancel fee” filters to find flights that won’t charge extra if you need to alter your plans. To update your itinerary, head to “Trips,” select your flight and click on “Manage Booking” for further information.