$122 Cheap American Airlines flights Columbus (CMH) to Fort Myers (RSW)

Grab cheap round-trip American Airlines flights from $331 from CMH to RSW by filtering your results from “Price (lowest to highest)” on Expedia. Or look for options from $122 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for round-trip or one-way flights to Fort Myers in August or September. You could find an affordable fare with American Airlines during these off-peak months.

Search for affordable American Airlines flights from John Glenn Columbus Intl. Airport (CMH) to Southwest Florida Intl. Airport (RSW) one to three months before your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and itinerary, the best day of the week to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To see if there’s a direct journey from CMH to RSW with American Airlines or other airlines, use our “Nonstop” filter when browsing for tickets.

Search American Airlines’s earliest flights from CMH to RSW by using the “Early Morning” and “Morning” filters. Not only will you arrive at your destination sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Southwest Florida Intl. Airport (RSW) is the main Fort Myers gateway for American Airlines flights from John Glenn Columbus Intl. Airport (CMH).

Depending on the ticket type you purchased, a fee may apply if you cancel or change your booking more than 24 hours after it has been confirmed. To find flexible fares, select our “No cancel fee” or “Changes included” filter when you look for flights. For more details on canceling or modifying your reservation, visit “Trips,” select your flight and click on “Manage Booking.”