$100 Cheap American Airlines flights Jacksonville (JAX) to Roanoke (ROA)

Landing cheap one-way American Airlines flights from JAX to ROA from $100 on Expedia couldn’t be simpler — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly round-trip fares from $214 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the cheapest months to travel to Roanoke with American Airlines. You could also find great deals on one-way and round-trip fares in February.

Begin your search one to three months ahead of your travel date to get cheap fares on American Airlines flights from Jacksonville Intl. Airport (JAX) to Roanoke Regional Airport (ROA). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Nail your timing, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on our “Nonstop” filter when looking for direct American Airlines flights from JAX to ROA. It’s also a good way to compare other airlines servicing the same nonstop trip.

To find the earliest departures from JAX to ROA with American Airlines, sort your results by “Early Morning” and “Morning.” Booking an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Jacksonville Intl. Airport (JAX) to Roanoke arrive at Roanoke Regional Airport (ROA). This is the main gateway to this destination.

Depending on the type of fare you purchased, a fee may apply if you cancel or reschedule your flight more than 24 hours after it’s been confirmed. To secure tickets with more flexibility, select our “Changes included” and “No cancel fee” boxes when looking for flights. For more details on canceling or changing your reservation, visit “Trips,” select your flight and tick “Manage Booking.”